Protein: ARF1
ADP-ribosylation factor 1 (EC 3.6.5.2)

Gene: ARF1
Organism: Saccharomyces cerevisiae S288C
Interactions: 153
UniProt ID: P11076

Gene Ontology (top 5):
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

536071

ARF2
ADP-ribosylation factor 2

5

17

Small-scale

0.922

High

536063

ARF1
ADP-ribosylation factor 1

5

17

Small-scale

0.916

High

536187

CHS5
Chitin biosynthesis protein CHS5

4

1

Small-scale

0.906

High

536127

GEA2
ARF guanine-nucleotide exchange factor 2

5

12

Small-scale

0.900

High

536102

GCS1
ADP-ribosylation factor GTPase-activating protein GCS1

4

20

Small-scale

0.888

High

536116

GLO3
ADP-ribosylation factor GTPase-activating protein GLO3

3

20

Small-scale

0.854

High

536133

COPB2
Coatomer subunit beta'

3

12

Small-scale

0.834

High

536138

COPD
Coatomer subunit delta

2

7

Small-scale

0.800

High

536173

GGA1
ADP-ribosylation factor-binding protein GGA1

2

20

Small-scale

0.793

High

536090

COPG
Coatomer subunit gamma

2

20

Small-scale

0.786

High

536104

AP1B1
AP-1 complex subunit beta-1

2

20

Small-scale

0.768

High

536132

COPB
Coatomer subunit beta

2

20

Small-scale

0.768

High

535967

SEC7
ADP-ribosylation factor guanine nucleotide-exchange factor SEC7

2

15

Small-scale

0.754

High

536150

COPA
Coatomer subunit alpha

2

12

Small-scale

0.754

High

536122

AKR1
Palmitoyltransferase AKR1

1

2

High-throughput

0.698

High

536131

CHS6
Chitin biosynthesis protein CHS6

3

3

Small-scale

0.676

High

536140

AP3B
AP-3 complex subunit beta

1

20

Small-scale

0.647

High

536184

AP3D
AP-3 complex subunit delta

1

20

Small-scale

0.647

High

536186

AP1G1
AP-1 complex subunit gamma-1

1

20

Small-scale

0.647

High

536079

BET1
Protein transport protein BET1

3

2

Small-scale

0.640

High

403322

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

2

2

Small-scale

0.625

High

536110

GBLP
Small ribosomal subunit protein RACK1

1

4

Small-scale

0.618

High

536143

GEA1
ARF guanine-nucleotide exchange factor 1

1

14

Small-scale

0.618

High

536176

SYT1
Arf guanine nucleotide exchange factor SYT1

1

14

Small-scale

0.618

High

536195

CMR1
DNA damage-binding protein CMR1

1

3

High-throughput

0.618

High

536149

COPZ
Coatomer subunit zeta

2

11

High-throughput

0.614

High

536119

GGA2
ADP-ribosylation factor-binding protein GGA2

2

20

Small-scale

0.614

High

536075

EPT1
Choline/ethanolaminephosphotransferase 1

2

2

High-throughput

0.608

High

536108

BCH2
Protein BCH2

2

3

Small-scale

0.588

High

536167

BCH1
Protein BCH1

2

3

Small-scale

0.588

High

536183

BUD7
Bud site selection protein 7

2

3

Small-scale

0.588

High

536076

SEC22
Protein transport protein SEC22

2

4

Small-scale

0.584

High

536105

YKT6
Synaptobrevin homolog YKT6

2

4

Small-scale

0.584

High

536137

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

3

High-throughput

0.584

High

522854

HSP71
Heat shock protein SSA1

2

6

High-throughput

0.571

High

525745

HSP72
Heat shock protein SSA2

2

6

High-throughput

0.571

High

536083

MAS5
Mitochondrial protein import protein MAS5

2

3

High-throughput

0.571

High

536179

TLG2
t-SNARE affecting a late Golgi compartment protein 2

2

10

Small-scale

0.571

High

536178

VPS13
Intermembrane lipid transfer protein VPS13

1

5

Small-scale

0.561

High

536188

RUD3
GRIP domain-containing protein RUD3

1

3

Small-scale

0.561

High

536082

BOS1
Protein transport protein BOS1

2

0

Small-scale

0.559

High

376262

YPT1
GTP-binding protein YPT1

1

18

High-throughput

0.541

High

536091

HXT1
Low-affinity glucose transporter HXT1

1

3

High-throughput

0.541

High

536111

BAP2
Leu/Val/Ile amino-acid permease

1

4

High-throughput

0.541

High

536113

SFT2
Protein transport protein SFT2

1

1

High-throughput

0.541

High

536129

QDR2
Quinidine resistance protein 2

1

2

High-throughput

0.541

High

536135

LEM3
Phospholipid-transporting ATPase accessory subunit LEM3

1

1

High-throughput

0.541

High

536151

CYP8
Peptidyl-prolyl cis-trans isomerase CYP8

1

1

High-throughput

0.541

High

536154

TMEDA
Endoplasmic reticulum vesicle protein 25

1

11

High-throughput

0.541

High

536162

TVP15
Golgi apparatus membrane protein TVP15

1

1

High-throughput

0.541

High

536169

ERP1
Protein ERP1

1

10

High-throughput

0.541

High

536175

TPO3
Polyamine transporter 3

1

3

High-throughput

0.541

High

448620

SNF1
Carbon catabolite-derepressing protein kinase

1

3

High-throughput

0.536

High

536099

PXA2
Peroxisomal long-chain fatty acid import protein 1

1

5

High-throughput

0.532

High

536134

PXA1
Peroxisomal long-chain fatty acid import protein 2

1

3

High-throughput

0.532

High

536130

COPE
Coatomer subunit epsilon

1

0

Small-scale

0.527

High

536136

EMP47
Protein EMP47

1

0

High-throughput

0.518

High

536148

ERV29
ER-derived vesicles protein ERV29

1

0

High-throughput

0.518

High

536160

GOT1
Protein transport protein GOT1

1

0

High-throughput

0.518

High

536161

ANY1
Scramblase ANY1

1

0

High-throughput

0.518

High

536180

BSC6
Bypass of stop codon protein 6

1

0

High-throughput

0.518

High

536190

RBD2
Rhomboid-type serine protease 2

1

0

High-throughput

0.518

High

536196

YB029
UPF0768 protein YBL029C-A

1

0

High-throughput

0.518

High

517855

SSBP1
Single-stranded nucleic acid-binding protein

1

5

High-throughput

0.501

High

536081

KIN82
Serine/threonine-protein kinase KIN82

1

3

High-throughput

0.501

High

536123

PIK1
Phosphatidylinositol 4-kinase PIK1

1

2

Small-scale

0.501

High

536174

VPS74
Vacuolar protein sorting-associated protein 74

1

1

Small-scale

0.501

High

536181

GYP1
GTPase-activating protein GYP1

1

9

Small-scale

0.501

High

394154

EF1A
Elongation factor 1-alpha

1

4

High-throughput

0.500

High

536074

CLH
Clathrin heavy chain

1

2

High-throughput

0.500

High

536101

TSA1
Peroxiredoxin TSA1

1

2

High-throughput

0.500

High

484259

KEX1
Pheromone-processing carboxypeptidase KEX1

1

1

High-throughput

0.494

High

536095

TMN1
Transmembrane 9 superfamily member 1

1

5

High-throughput

0.494

High

536112

YB91
Probable metabolite transport protein YBR241C

1

12

High-throughput

0.494

High

536152

ALO
D-arabinono-1,4-lactone oxidase

1

1

High-throughput

0.494

High

458988

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

1

High-throughput

0.489

High

536120

GPI16
GPI transamidase component GPI16

1

1

High-throughput

0.489

High

367664

ENO1
Enolase 1

1

0

High-throughput

0.479

High

536068

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.479

High

536100

BMH2
Protein BMH2

1

0

High-throughput

0.479

High

536139

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

0

High-throughput

0.479

High

392105

HSP82
ATP-dependent molecular chaperone HSP82

1

6

High-throughput

0.479

High

420871

PMA1
Plasma membrane ATPase 1

1

3

High-throughput

0.479

High

452466

PUR2
Bifunctional purine biosynthetic protein ADE5,7 [Includes: Phosphoribosylamine--glycine ligase

1

1

High-throughput

0.479

High

518176

IF4A
ATP-dependent RNA helicase eIF4A

1

2

High-throughput

0.479

High

536065

RNA1
Ran GTPase-activating protein 1

1

1

High-throughput

0.479

High

536066

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.479

High

536069

HSC82
ATP-dependent molecular chaperone HSC82

1

6

High-throughput

0.479

High

536072

SRP54
Signal recognition particle subunit SRP54

1

1

High-throughput

0.479

High

536073

VPS1
Vacuolar protein sorting-associated protein 1

1

2

High-throughput

0.479

High

536077

KCC2
Calcium/calmodulin-dependent protein kinase II

1

1

High-throughput

0.479

High

536078

TRX2
Thioredoxin-2

1

2

Small-scale

0.479

High

536080

SIS1
Protein SIS1

1

5

High-throughput

0.479

High

536084

CDC48
Cell division control protein 48

1

5

High-throughput

0.479

High

536087

XPO1
Exportin-1

1

2

High-throughput

0.479

High

536088

SNC1
Synaptobrevin homolog 1

1

9

Small-scale

0.479

High

536089

HS104
Heat shock protein 104

1

2

High-throughput

0.479

High

536092

HOG1
Mitogen-activated protein kinase HOG1

1

3

High-throughput

0.479

High

536096

SSO1
Protein SSO1

1

8

Small-scale

0.479

High

536098

PRS6A
26S proteasome regulatory subunit 6A

1

6

High-throughput

0.479

High

536109

VPP2
V-type proton ATPase subunit a, Golgi isoform

1

3

Small-scale

0.479

High

536117

GOSR1
Golgi SNAP receptor complex member 1

1

2

High-throughput

0.479

High

536118

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.479

High

536121

RPN10
26S proteasome regulatory subunit RPN10

1

2

High-throughput

0.479

High

536125

SSO2
Protein SSO2

1

8

Small-scale

0.479

High

536126

SIT1
Siderophore iron transporter 1

1

2

High-throughput

0.479

High

536142

MPS3
Spindle pole body assembly component MPS3

1

1

High-throughput

0.479

High

536153

VPS9
Vacuolar protein sorting-associated protein 9

1

2

Small-scale

0.479

High

536155

UFD2
E4 ubiquitin-protein ligase UFD2

1

1

High-throughput

0.479

High

536156

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

3

High-throughput

0.479

High

536157

SED5
Integral membrane protein SED5

1

10

Small-scale

0.479

High

536171

IMB1
Importin subunit beta-1

1

1

High-throughput

0.479

High

536177

SUB2
ATP-dependent RNA helicase SUB2

1

3

High-throughput

0.479

High

536189

VAM3
Syntaxin VAM3

1

8

Small-scale

0.479

High

434751

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

536093

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

0

Small-scale

0.458

High

536097

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

536107

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

0

High-throughput

0.458

High

536124

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

536170

SYRC
Arginine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

536070

CPT1
Cholinephosphotransferase 1

1

2

High-throughput

0.457

High

536146

YG3A
Uncharacterized protein YGR130C

1

9

High-throughput

0.457

High

536164

ERV41
ER-derived vesicles protein ERV41

1

4

High-throughput

0.457

High

440886

CDC7
Cell division control protein 7

1

7

Small-scale

0.445

High

536064

SSB1
Ribosome-associated molecular chaperone SSB1

1

6

High-throughput

0.445

High

536094

HSP7F
Heat shock protein homolog SSE1

1

9

High-throughput

0.445

High

536128

SSB2
Ribosome-associated molecular chaperone SSB2

1

6

High-throughput

0.445

High

536145

PFD3
Prefoldin subunit 3

1

1

High-throughput

0.445

High

536158

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

1

High-throughput

0.445

High

536115

FTH1
Iron transporter FTH1

1

0

High-throughput

0.438

High

536141

ATG27
Autophagy-related protein 27

1

0

High-throughput

0.438

High

536168

DFG5
Mannan endo-1,6-alpha-mannosidase DFG5

1

0

High-throughput

0.438

High

536086

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

536163

RUVB1
RuvB-like protein 1

1

3

High-throughput

0.437

High

536193

RUVB2
RuvB-like protein 2

1

3

High-throughput

0.437

High

536144

HLJ1
Protein HLJ1

1

3

High-throughput

0.407

High

536194

CAF1A
Chromatin assembly factor 1 subunit A

1

1

High-throughput

0.407

High

536067

SNA3
Protein SNA3

1

0

High-throughput

0.282

High

536159

OSTD
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1

1

0

High-throughput

0.282

High

536185

VPS68
Vacuolar protein sorting-associated protein 68

1

0

High-throughput

0.282

High

536192

PEX11
Peroxisomal membrane protein PMP27

1

0

High-throughput

0.282

High

536085

MGMT
Methylated-DNA--protein-cysteine methyltransferase

1

0

High-throughput

0.279

Low

536103

CBF3C
Centromere DNA-binding protein complex CBF3 subunit C

1

0

High-throughput

0.279

Low

536165

SEN15
tRNA-splicing endonuclease subunit SEN15

1

0

High-throughput

0.279

Low

536191

IES3
Ino eighty subunit 3

1

0

High-throughput

0.279

Low

536147

YG3W
Uncharacterized protein YGR168C

1

0

Small-scale

0.251

Low

536114

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.249

Low

536166

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.249

Low

536172

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

536182

ESA1
Histone acetyltransferase ESA1

1

0

Small-scale

0.249

Low

536197

ENV10
SRP-independent targeting protein 2

1

0

High-throughput

0.249

Low

536106

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025