Interactor 1: FPPS (P14324)
Farnesyl pyrophosphate synthase (FPP synthase) (FPS) (EC 2.5.1.10) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Geranyltranstransferase)
Gene: FDPS

Interactor 2: FPPS (P14324)
Farnesyl pyrophosphate synthase (FPP synthase) (FPS) (EC 2.5.1.10) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Geranyltranstransferase)
Gene: FDPS

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 16684881
Identification Methods x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains polyprenyl_synt~polyprenyl_synt
Common GO terms GO:0003723 - RNA binding
GO:0004161 - dimethylallyltranstransferase activity
GO:0004337 - geranyltranstransferase activity
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 5 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 419
Hs

1 419
+ Hs
+ Sp
+ Sp
+ Sp
+ At
+ Ec
+ Hs
+ Sc
+ Ec
+ Hp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024