HitPredict

Interactor 1: TRI27 (P14373)
Zinc finger protein RFP (EC 2.3.2.27) (RING finger protein 76) (Ret finger protein) (Tripartite motif-containing protein 27)
Gene: TRIM27

Interactor 2: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	36111389
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005829 - cytosol and 2 others more... GO:0008270 - zinc ion binding GO:0016605 - PML body
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 513 Hs			1 440
+	Hs
		584950 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		1036807 TRI11_HUMAN (1-500): 9.03e-148: 433: 38.00		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		1036876 TRIM5_HUMAN (1-494): 9.4e-127: 380: 29.15		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		1036706 TRI50_HUMAN (1-488): 4.24e-121: 365: 27.53		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Mm
		548985 TR30A_MOUSE (1-494): 1.14e-111: 341: 24.62		SQSTM_MOUSE (1-440): 0: 731: 90.72
+	Hs
		1019298 TRI26_HUMAN (385-482): 2.75e-09: 61.6: 40.40		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		584963 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78