HitPredict

Interactor 1: TRI27 (P14373)
Zinc finger protein RFP (EC 2.3.2.27) (RING finger protein 76) (Ret finger protein) (Tripartite motif-containing protein 27)
Gene: TRIM27

Interactor 2: TRI43 (Q96BQ3)
Tripartite motif-containing protein 43
Gene: TRIM43

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	22493164
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	PRY~SPRY, SPRY~SPRY, zf-C3HC4_4~zf-C3HC4_4
Common GO terms	GO:0005737 - cytoplasm GO:0008270 - zinc ion binding GO:0045087 - innate immune response GO:0061630 - ubiquitin protein ligase activity
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 513 Hs			1 446
+	Hs
		536726 TRI27_HUMAN (1-513): 0: 523: 100.00		RO52_HUMAN (1-444): 2.13e-143: 420: 32.74
+	Hs
		536980 TRI27_HUMAN (1-513): 0: 523: 100.00		TRI11_HUMAN (2-445): 7.79e-137: 403: 32.67
+	Hs
		536717 TRI27_HUMAN (1-513): 0: 523: 100.00		TRI27_HUMAN (1-444): 5.57e-131: 389: 25.52
+	Hs
		584870 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		RO52_HUMAN (1-444): 2.13e-143: 420: 32.74
+	Hs
		585075 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		TRI39_HUMAN (6-446): 6.79e-141: 415: 28.78
+	Hs
		1336382 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		TRI39_HUMAN (6-446): 6.79e-141: 415: 28.78
+	Hs
		536904 TRI27_HUMAN (1-513): 0: 523: 100.00		TRI50_HUMAN (5-445): 1.22e-110: 336: 18.66
+	Hs
		1290865 TRI11_HUMAN (1-500): 9.03e-148: 433: 38.00		TRI11_HUMAN (2-445): 7.79e-137: 403: 32.67
+	Mm
		1112402 RO52_MOUSE (3-492): 8.38e-148: 433: 34.55		Q3U7K7_MOUSE (5-444): 3.28e-134: 396: 29.75
+	Hs
		1336392 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		TRI17_HUMAN (2-444): 1.25e-116: 351: 29.44
+	Hs
		585058 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		TRIM5_HUMAN (1-443): 4.32e-114: 345: 24.43
+	Hs
		1245269 TRI58_HUMAN (1-493): 2.59e-145: 427: 34.00		TRI58_HUMAN (1-443): 1.16e-128: 382: 29.74
+	Hs
		1290900 TRI11_HUMAN (1-500): 9.03e-148: 433: 38.00		TRI10_HUMAN (1-446): 9.32e-109: 331: 25.21
+	Hs
		1290906 TRI11_HUMAN (1-500): 9.03e-148: 433: 38.00		TRI35_HUMAN (3-445): 2.81e-96: 299: 22.63
+	Hs
		537046 TRI27_HUMAN (1-513): 0: 523: 100.00		TRI31_HUMAN (5-270): 4.54e-28: 117: 29.21
+	Hs
		585057 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		TRI31_HUMAN (5-270): 4.54e-28: 117: 29.21