HitPredict

Interactor 1: TRI27 (P14373)
Zinc finger protein RFP (EC 2.3.2.27) (RING finger protein 76) (Ret finger protein) (Tripartite motif-containing protein 27)
Gene: TRIM27

Interactor 2: UBE2Z (Q9H832)
Ubiquitin-conjugating enzyme E2 Z (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme Z) (Uba6-specific E2 conjugating enzyme 1) (Use1) (Ubiquitin carrier protein Z) (Ubiquitin-protein ligase Z)
Gene: UBE2Z

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	19549727
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 513 Hs			1 354
+	Hs
		537142 TRI27_HUMAN (1-513): 0: 523: 100.00		UB2D4_HUMAN (99-253): 1.41e-72: 223: 33.12
+	Hs
		536779 TRI27_HUMAN (1-513): 0: 523: 100.00		UB2D2_HUMAN (99-253): 3.54e-72: 222: 34.40
+	Hs
		536760 TRI27_HUMAN (1-513): 0: 523: 100.00		UB2D1_HUMAN (99-253): 2.91e-71: 220: 31.85
+	Hs
		536772 TRI27_HUMAN (1-513): 0: 523: 100.00		UB2D3_HUMAN (99-253): 7.74e-71: 219: 34.40
+	Hs
		536996 TRI27_HUMAN (1-513): 0: 523: 100.00		UB2E2_HUMAN (44-253): 2.74e-65: 207: 24.53
+	Hs
		536965 TRI27_HUMAN (1-513): 0: 523: 100.00		UB2E3_HUMAN (74-253): 5.35e-65: 206: 27.47
+	Hs
		536763 TRI27_HUMAN (1-513): 0: 523: 100.00		UB2E1_HUMAN (82-253): 6.89e-65: 205: 27.01
+	Hs
		537082 TRI27_HUMAN (1-513): 0: 523: 100.00		UBE2T_HUMAN (99-291): 1.1e-61: 197: 27.14
+	Hs
		584923 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		UB2D2_HUMAN (99-253): 3.54e-72: 222: 34.40
+	Hs
		584907 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		UB2D1_HUMAN (99-253): 2.91e-71: 220: 31.85
+	Hs
		584916 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		UB2D3_HUMAN (99-253): 7.74e-71: 219: 34.40
+	Hs
		849453 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		UB2D1_HUMAN (99-253): 2.91e-71: 220: 31.85
+	Hs
		895921 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		UB2D3_HUMAN (99-253): 7.74e-71: 219: 34.40
+	Hs
		584910 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		UB2E1_HUMAN (82-253): 6.89e-65: 205: 27.01
+	Hs
		851889 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		UB2E1_HUMAN (82-253): 6.89e-65: 205: 27.01
+	Hs
		584902 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		UB2R1_HUMAN (96-283): 9.14e-57: 186: 26.36
+	Hs
		537049 TRI27_HUMAN (1-513): 0: 523: 100.00		UBE2O_HUMAN (104-242): 7.06e-21: 96.3: 40.14
+	Hs
		536774 TRI27_HUMAN (1-513): 0: 523: 100.00		UBE2N_HUMAN (103-226): 3.77e-18: 82: 36.29
+	Hs
		584918 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		UBE2N_HUMAN (103-226): 3.77e-18: 82: 36.29
+	Hs
		896547 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		UBE2N_HUMAN (103-226): 3.77e-18: 82: 36.29