HitPredict

Interactor 1: NCF1 (P14598)
Neutrophil cytosol factor 1 (NCF-1) (47 kDa autosomal chronic granulomatous disease protein) (47 kDa neutrophil oxidase factor) (NCF-47K) (Neutrophil NADPH oxidase factor 1) (Nox organizer 2) (Nox-organizing protein 2) (SH3 and PX domain-containing protein 1A) (p47-phox)
Gene: NCF1

Interactor 2: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.629

Property	Details
Experiments	11027608, 16375898
Identification Methods	far western blotting, pull down, filter binding
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 390 Hs			1 375
+	Hs
		537618 NCF1_HUMAN (1-390): 1.2e-102: 310: 100.00		ACTA_HUMAN (2-375): 0: 591: 94.12
+	Hs
		929929 NOXO1_HUMAN (26-382): 3.31e-35: 134: 23.45		ACTG_HUMAN (1-375): 0: 601: 98.93
+	Hs
		891762 SRC8_HUMAN (4-282): 7.5e-33: 131: 12.67		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Hs
		929863 SRC8_HUMAN (4-282): 7.5e-33: 131: 12.67		ACTG_HUMAN (1-375): 0: 601: 98.93
+	Hs
		929985 SH3G2_HUMAN (6-211): 5.16e-32: 125: 10.68		ACTG_HUMAN (1-375): 0: 601: 98.93
+	Hs
		932154 SRC8_HUMAN (4-282): 7.5e-33: 131: 12.67		ACTC_HUMAN (2-375): 0: 592: 94.12
+	Hs
		891821 SH319_HUMAN (81-282): 8.99e-15: 77.9: 17.83		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Hs
		235496 VINEX_HUMAN (85-388): 1.86e-14: 77: 12.95		ACTS_HUMAN (2-375): 0: 592: 93.58
+	Hs
		933003 DNMBP_HUMAN (161-281): 1.1e-12: 71.7: 19.23		ACTS_HUMAN (2-375): 0: 592: 93.58
+	Hs
		932316 SH3K1_HUMAN (232-302): 3.59e-09: 60.6: 21.13		ACTC_HUMAN (2-375): 0: 592: 94.12