Protein: MCFD2
Multiple coagulation factor deficiency protein 2 (Neural stem cell-derived neuronal survival protein)

Gene: MCFD2
Organism: Homo sapiens
Interactions: 103
UniProt ID: Q8NI22

Gene Ontology (top 5):
GO:0005509 - calcium ion binding
GO:0005789 - endoplasmic reticulum membrane
GO:0005794 - Golgi apparatus
GO:0012507 - ER to Golgi transport vesicle membrane
GO:0015031 - protein transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

825478

LMAN1
Protein ERGIC-53

8

0

Small-scale

0.922

High

136191

SCD
Stearoyl-CoA desaturase

2

0

High-throughput

0.580

High

870028

LIPR1
Inactive pancreatic lipase-related protein 1

2

0

High-throughput

0.580

High

943595

S35A1
CMP-sialic acid transporter

2

0

High-throughput

0.580

High

502342

BIP
Endoplasmic reticulum chaperone BiP

2

0

High-throughput

0.576

High

1246308

SCYL1
N-terminal kinase-like protein

1

1

High-throughput

0.575

High

1246319

TMX1
Thioredoxin-related transmembrane protein 1

1

1

High-throughput

0.575

High

945866

NUCB2
Nucleobindin-2

1

0

High-throughput

0.546

High

1070870

RCN1
Reticulocalbin-1

1

0

High-throughput

0.546

High

1246311

ERP44
Endoplasmic reticulum resident protein 44

1

0

High-throughput

0.546

High

863496

COPA
Coatomer subunit alpha

1

1

High-throughput

0.536

High

1246330

COPG2
Coatomer subunit gamma-2

1

1

High-throughput

0.536

High

149690

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.513

High

308906

KI20A
Kinesin-like protein KIF20A

1

0

High-throughput

0.513

High

878210

SEC13
Protein SEC13 homolog

1

0

High-throughput

0.513

High

902342

COPZ1
Coatomer subunit zeta-1

1

0

High-throughput

0.513

High

1246304

YIPF5
Protein YIPF5

1

0

High-throughput

0.513

High

1246328

KLHL9
Kelch-like protein 9

1

1

High-throughput

0.489

High

1246329

KLH13
Kelch-like protein 13

1

1

High-throughput

0.489

High

297769

MICA2
[F-actin]-monooxygenase MICAL2

1

0

High-throughput

0.481

High

532174

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

High-throughput

0.481

High

822100

KC1A
Casein kinase I isoform alpha

1

0

High-throughput

0.481

High

395265

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

205717

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

48430

ESYT2
Extended synaptotagmin-2

1

1

High-throughput

0.445

High

258951

RTN2
Reticulon-2

1

2

High-throughput

0.445

High

307075

RTN3
Reticulon-3

1

2

High-throughput

0.445

High

310730

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

1

High-throughput

0.445

High

653669

CALR
Calreticulin

1

1

High-throughput

0.445

High

654576

CALX
Calnexin

1

1

High-throughput

0.445

High

725502

COPB2
Coatomer subunit beta'

1

1

High-throughput

0.445

High

833274

TMEDA
Transmembrane emp24 domain-containing protein 10

1

2

High-throughput

0.445

High

1071797

TMED2
Transmembrane emp24 domain-containing protein 2

1

2

High-throughput

0.445

High

1120963

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

2

High-throughput

0.445

High

1224251

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

1

High-throughput

0.445

High

1246303

ATLA1
Atlastin-1

1

2

High-throughput

0.445

High

1246312

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.445

High

1246321

RTN4
Reticulon-4

1

2

High-throughput

0.445

High

1246327

VAPA
Vesicle-associated membrane protein-associated protein A

1

1

High-throughput

0.445

High

1246332

DHRS7
Dehydrogenase/reductase SDR family member 7

1

1

High-throughput

0.445

High

1246333

TMED5
Transmembrane emp24 domain-containing protein 5

1

2

High-throughput

0.445

High

1246335

COPG1
Coatomer subunit gamma-1

1

1

High-throughput

0.445

High

50196

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.426

High

58118

NBAS
NBAS subunit of NRZ tethering complex

1

0

High-throughput

0.426

High

199366

ZW10
Centromere/kinetochore protein zw10 homolog

1

0

High-throughput

0.426

High

202932

EMC8
ER membrane protein complex subunit 8

1

0

High-throughput

0.426

High

266210

ERLN1
Erlin-1

1

0

High-throughput

0.426

High

335477

NB5R3
NADH-cytochrome b5 reductase 3

1

0

High-throughput

0.426

High

818982

COPD
Coatomer subunit delta

1

0

High-throughput

0.426

High

847563

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.426

High

863276

COPB
Coatomer subunit beta

1

0

High-throughput

0.426

High

924083

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

0

High-throughput

0.426

High

950662

ARF5
ADP-ribosylation factor 5

1

0

High-throughput

0.426

High

1058487

GANAB
Neutral alpha-glucosidase AB

1

0

High-throughput

0.426

High

1062592

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.426

High

1065279

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

0

High-throughput

0.426

High

1065394

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

0

High-throughput

0.426

High

1072927

DHC24
Delta(24)-sterol reductase

1

0

High-throughput

0.426

High

1077678

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

0

High-throughput

0.426

High

1165396

LCLT1
Lysocardiolipin acyltransferase 1

1

0

High-throughput

0.426

High

1234663

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

0

High-throughput

0.426

High

1236924

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.426

High

1243329

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.426

High

1246302

SCFD1
Sec1 family domain-containing protein 1

1

0

High-throughput

0.426

High

1246305

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

0

High-throughput

0.426

High

1246306

ASTRA
Protein Aster-A

1

0

High-throughput

0.426

High

1246313

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.426

High

1246316

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.426

High

1246318

RBGPR
Rab3 GTPase-activating protein non-catalytic subunit

1

0

High-throughput

0.426

High

1246322

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.426

High

1246326

TECR
Very-long-chain enoyl-CoA reductase

1

0

High-throughput

0.426

High

99806

F5H6I7
Atlastin GTPase 3

1

2

High-throughput

0.407

High

1240214

DHB11
Estradiol 17-beta-dehydrogenase 11

1

2

High-throughput

0.407

High

1245521

ATLA2
Atlastin-2

1

2

High-throughput

0.407

High

965952

ILRL1
Interleukin-1 receptor-like 1

2

0

High-throughput

0.316

High

1067541

P2RY6
P2Y purinoceptor 6

2

0

High-throughput

0.316

High

1231607

SYS1
Protein SYS1 homolog

2

0

High-throughput

0.316

High

1246307

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

2

0

High-throughput

0.316

High

1103138

HKDC1
Hexokinase HKDC1

1

0

High-throughput

0.279

Low

413158

CCKN
Cholecystokinin

1

0

High-throughput

0.268

Low

527646

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.268

Low

1246331

SHLB1
Endophilin-B1

1

0

High-throughput

0.268

Low

1062040

CLCA4
Calcium-activated chloride channel regulator 4

1

0

High-throughput

0.251

Low

659729

RXRB
Retinoic acid receptor RXR-beta

1

0

High-throughput

0.249

Low

1246315

UBXN6
UBX domain-containing protein 6

1

0

Small-scale

0.249

Low

201040

VIP2
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

1

0

High-throughput

0.232

Low

277096

STAM2
Signal transducing adapter molecule 2

1

0

High-throughput

0.232

Low

432821

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

0

High-throughput

0.232

Low

827817

AL7A1
Alpha-aminoadipic semialdehyde dehydrogenase

1

0

High-throughput

0.232

Low

847313

SSRD
Translocon-associated protein subunit delta

1

0

High-throughput

0.232

Low

961744

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.232

Low

1026732

PRDX4
Peroxiredoxin-4

1

0

High-throughput

0.232

Low

1174512

UB2R2
Ubiquitin-conjugating enzyme E2 R2

1

0

High-throughput

0.232

Low

1243767

VP37A
Vacuolar protein sorting-associated protein 37A

1

0

High-throughput

0.232

Low

1246309

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.232

Low

1246310

PXL2A
Peroxiredoxin-like 2A

1

0

High-throughput

0.232

Low

1246314

WDR11
WD repeat-containing protein 11

1

0

High-throughput

0.232

Low

1246317

RGAP1
Rac GTPase-activating protein 1

1

0

High-throughput

0.232

Low

1246320

APMAP
Adipocyte plasma membrane-associated protein

1

0

High-throughput

0.232

Low

1246323

TM38B
Trimeric intracellular cation channel type B

1

0

High-throughput

0.232

Low

1246324

GPTC2
G patch domain-containing protein 2

1

0

High-throughput

0.232

Low

1246325

PSD3
PH and SEC7 domain-containing protein 3

1

0

High-throughput

0.232

Low

1246334

SERC
Phosphoserine aminotransferase

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024