HitPredict

Interactor 1: NCF1 (P14598)
Neutrophil cytosol factor 1 (NCF-1) (47 kDa autosomal chronic granulomatous disease protein) (47 kDa neutrophil oxidase factor) (NCF-47K) (Neutrophil NADPH oxidase factor 1) (Nox organizer 2) (Nox-organizing protein 2) (SH3 and PX domain-containing protein 1A) (p47-phox)
Gene: NCF1

Interactor 2: ACTA (P62736)
Actin, aortic smooth muscle (EC 3.6.4.-) (Alpha-actin-2) (Cell growth-inhibiting gene 46 protein) [Cleaved into: Actin, aortic smooth muscle, intermediate form]
Gene: ACTA2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15618548
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 390 Hs			1 377
+	Hs
		537617 NCF1_HUMAN (1-390): 1.2e-102: 310: 100.00		ACTB_HUMAN (4-377): 0: 598: 94.12
+	Hs
		929929 NOXO1_HUMAN (26-382): 3.31e-35: 134: 23.45		ACTG_HUMAN (4-377): 0: 598: 94.39
+	Hs
		891762 SRC8_HUMAN (4-282): 7.5e-33: 131: 12.67		ACTB_HUMAN (4-377): 0: 598: 94.12
+	Hs
		929863 SRC8_HUMAN (4-282): 7.5e-33: 131: 12.67		ACTG_HUMAN (4-377): 0: 598: 94.39
+	Hs
		932154 SRC8_HUMAN (4-282): 7.5e-33: 131: 12.67		ACTC_HUMAN (1-377): 0: 598: 98.41
+	Hs
		929985 SH3G2_HUMAN (6-211): 5.16e-32: 125: 10.68		ACTG_HUMAN (4-377): 0: 598: 94.39
+	Hs
		891821 SH319_HUMAN (81-282): 8.99e-15: 77.9: 17.83		ACTB_HUMAN (4-377): 0: 598: 94.12
+	Hs
		235496 VINEX_HUMAN (85-388): 1.86e-14: 77: 12.95		ACTS_HUMAN (1-377): 0: 598: 97.88
+	Hs
		933003 DNMBP_HUMAN (161-281): 1.1e-12: 71.7: 19.23		ACTS_HUMAN (1-377): 0: 598: 97.88
+	Hs
		932316 SH3K1_HUMAN (232-302): 3.59e-09: 60.6: 21.13		ACTC_HUMAN (1-377): 0: 598: 98.41