Interactor 1: NCF1 (P14598)
Neutrophil cytosol factor 1 (NCF-1) (47 kDa autosomal chronic granulomatous disease protein) (47 kDa neutrophil oxidase factor) (NCF-47K) (Neutrophil NADPH oxidase factor 1) (Nox organizer 2) (Nox-organizing protein 2) (SH3 and PX domain-containing protein 1A) (p47-phox)
Gene: NCF1

Interactor 2: NOXA1 (Q86UR1)
NADPH oxidase activator 1 (NOX activator 1) (Antigen NY-CO-31) (NCF2-like protein) (P67phox-like factor) (p51-nox)
Gene: NOXA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.621

The method score is based on:

Property Details
Experiments 16052631
Identification Methods two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains NECFESHC~SH3_1, SH3_1~p47_phox_C, PB1~SH3_1, SH3_1~SH3_1
Common GO terms GO:0005829 - cytosol
GO:0006801 - superoxide metabolic process
GO:0016176 - superoxide-generating NADPH oxidase activator activity
GO:0017124 - SH3 domain binding
GO:0042554 - superoxide anion generation
and 1 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 390
Hs

1 476
+ Hs
+ Hs
+ Hs
+ Mm

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Last updated: 15 Jul 2024