Protein: SNX21
Sorting nexin-21 (Sorting nexin L) (SNX-L)

Gene: SNX21
Organism: Homo sapiens
Interactions: 75
UniProt ID: Q969T3

Gene Ontology (top 5):
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding
GO:0015031 - protein transport
GO:0031901 - early endosome membrane
GO:0032266 - phosphatidylinositol-3-phosphate binding
GO:1901981 - phosphatidylinositol phosphate binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1281220

VP13B
Intermembrane lipid transfer protein VPS13B

2

2

High-throughput

0.628

High

331781

MTMR5
Myotubularin-related protein 5

1

1

High-throughput

0.618

High

1360610

MADD
MAP kinase-activating death domain protein

3

1

High-throughput

0.604

High

1034041

OCRL
Inositol polyphosphate 5-phosphatase OCRL

2

0

High-throughput

0.602

High

997070

TBA4A
Tubulin alpha-4A chain

2

2

High-throughput

0.574

High

1122758

DPOA2
DNA polymerase alpha subunit B

2

1

High-throughput

0.574

High

1259400

TBA1A
Tubulin alpha-1A chain

2

2

High-throughput

0.574

High

1381160

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

2

2

High-throughput

0.574

High

1381156

ATG2B
Autophagy-related protein 2 homolog B

1

2

High-throughput

0.536

High

1187957

PTHB1
Protein PTHB1

1

0

High-throughput

0.513

High

537658

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.489

High

931041

HSP72
Heat shock-related 70 kDa protein 2

1

3

High-throughput

0.489

High

1206998

ZNG1C
Zinc-regulated GTPase metalloprotein activator 1C

1

2

High-throughput

0.489

High

1307349

ZNG1B
Zinc-regulated GTPase metalloprotein activator 1B

1

2

High-throughput

0.489

High

1381159

TBA1C
Tubulin alpha-1C chain

1

2

High-throughput

0.489

High

422799

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

843839

HD
Huntingtin

3

0

High-throughput

0.345

High

1230755

HEAT6
HEAT repeat-containing protein 6

3

0

High-throughput

0.345

High

1381172

S4A7
Sodium bicarbonate cotransporter 3

3

0

High-throughput

0.345

High

607705

DCAM
S-adenosylmethionine decarboxylase proenzyme

2

0

High-throughput

0.328

High

878338

MRP
MARCKS-related protein

2

0

High-throughput

0.328

High

940493

DPOE2
DNA polymerase epsilon subunit 2

2

0

High-throughput

0.328

High

1081768

FP100
Fanconi anemia core complex-associated protein 100

2

0

High-throughput

0.328

High

1129968

MELK
Maternal embryonic leucine zipper kinase

2

0

High-throughput

0.328

High

1245050

TRI65
E3 ubiquitin-protein ligase TRIM65

2

0

High-throughput

0.328

High

1381157

DDX11
ATP-dependent DNA helicase DDX11

2

0

High-throughput

0.328

High

1381161

EIF2A
Eukaryotic translation initiation factor 2A

2

0

High-throughput

0.328

High

1381166

MKS1
Tectonic-like complex member MKS1

2

0

High-throughput

0.328

High

269331

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.316

High

1182851

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

2

0

High-throughput

0.314

High

1347800

SPT20
Spermatogenesis-associated protein 20

2

0

High-throughput

0.313

High

1035483

CX6A2
Cytochrome c oxidase subunit 6A2, mitochondrial

1

0

High-throughput

0.282

High

162113

ACOT8
Acyl-coenzyme A thioesterase 8

1

0

High-throughput

0.279

Low

191039

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.279

Low

231746

PEX1
Peroxisomal ATPase PEX1

1

0

High-throughput

0.279

Low

245511

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

0

High-throughput

0.279

Low

340015

RPA1
DNA-directed RNA polymerase I subunit RPA1

1

0

High-throughput

0.279

Low

389608

RET4
Retinol-binding protein 4

1

0

High-throughput

0.279

Low

391648

FRIH
Ferritin heavy chain

1

0

High-throughput

0.279

Low

565679

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

0

High-throughput

0.279

Low

772402

PCKGC
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]

1

0

High-throughput

0.279

Low

894481

PPOX
Protoporphyrinogen oxidase

1

0

High-throughput

0.279

Low

928645

PMS1
PMS1 protein homolog 1

1

0

High-throughput

0.279

Low

1065820

SLFN5
Schlafen family member 5

1

0

High-throughput

0.279

Low

1108654

TBB3
Tubulin beta-3 chain

1

0

High-throughput

0.279

Low

1180375

HKDC1
Hexokinase HKDC1

1

0

High-throughput

0.279

Low

1225959

F91A1
Protein FAM91A1

1

0

High-throughput

0.279

Low

1280123

SEN54
tRNA-splicing endonuclease subunit Sen54

1

0

High-throughput

0.279

Low

1312646

MSRB3
Methionine-R-sulfoxide reductase B3

1

0

High-throughput

0.279

Low

1315218

TRM44
Probable tRNA

1

0

High-throughput

0.279

Low

1322613

RPTOR
Regulatory-associated protein of mTOR

1

0

High-throughput

0.279

Low

1335483

SEN2
tRNA-splicing endonuclease subunit Sen2

1

0

High-throughput

0.279

Low

1336544

MROH1
Maestro heat-like repeat-containing protein family member 1

1

0

High-throughput

0.279

Low

1347952

NUBPL
Iron-sulfur cluster transfer protein NUBPL

1

0

High-throughput

0.279

Low

1371157

CLP1
Polyribonucleotide 5'-hydroxyl-kinase Clp1

1

0

High-throughput

0.279

Low

1381155

EME1
Structure-specific endonuclease subunit EME1

1

0

High-throughput

0.279

Low

1381162

TNG6
Transport and Golgi organization protein 6 homolog

1

0

High-throughput

0.279

Low

1381163

QTRT2
Queuine tRNA-ribosyltransferase accessory subunit 2

1

0

High-throughput

0.279

Low

1381167

MCM8
DNA helicase MCM8

1

0

High-throughput

0.279

Low

1381168

APC5
Anaphase-promoting complex subunit 5

1

0

High-throughput

0.279

Low

1381169

SARDH
Sarcosine dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1381170

DD19B
ATP-dependent RNA helicase DDX19B

1

0

High-throughput

0.279

Low

1381171

MTO1
5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial

1

0

High-throughput

0.279

Low

173178

XPO1
Exportin-1

1

0

High-throughput

0.249

Low

1254945

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

839490

PI4KA
Phosphatidylinositol 4-kinase alpha

1

0

High-throughput

0.232

Low

1029896

RUNX1
Runt-related transcription factor 1

1

0

High-throughput

0.232

Low

1126040

GAS6
Growth arrest-specific protein 6

1

0

High-throughput

0.232

Low

1219170

LYPL1
Lysophospholipase-like protein 1

1

0

High-throughput

0.232

Low

1248720

SBSN
Suprabasin

1

0

High-throughput

0.232

Low

1252818

NFXL1
NF-X1-type zinc finger protein NFXL1

1

0

High-throughput

0.232

Low

1324953

VW5B2
von Willebrand factor A domain-containing protein 5B2

1

0

High-throughput

0.232

Low

1381158

PCD16
Protocadherin-16

1

0

High-throughput

0.232

Low

1381164

RHOF
Rho-related GTP-binding protein RhoF

1

0

High-throughput

0.232

Low

1381165

TENS1
Tensin-1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025