HitPredict

Interactor 1: CYAA (P14605)
Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase) (Adenylyl cyclase)
Gene: cyr1

Interactor 2: GPA2 (Q04665)
Guanine nucleotide-binding protein alpha-2 subunit (GP2-alpha)
Gene: GPA2

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.857

The method score is based on:

Property Details
Experiments 15925945, 15831585, 24297439
Identification Methods pull down, two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains G-alpha~Guanylate_cyc
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005737 - cytoplasm
GO:0010515 - negative regulation of induction of conjugation with cellular fusion
GO:0010619 - adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1692
Sp

1 354
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024