HitPredict

Interactor 1: INSRR (P14616)
Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]
Gene: INSRR

Interactor 2: STIM1 (Q13586)
Stromal interaction molecule 1
Gene: STIM1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1297 Hs			1 685
+	Hs
		435635 IGF1R_HUMAN (9-1265): 0: 1222: 55.39		STIM1_HUMAN (1-685): 0: 1059: 100.00
+	Hs
		411379 INSR_HUMAN (27-1288): 0: 1183: 52.18		STIM1_HUMAN (1-685): 0: 1059: 100.00
+	Hs
		435788 IGF1R_HUMAN (9-1265): 0: 1222: 55.39		STIM2_HUMAN (49-643): 0: 826: 51.93
+	Hs
		411514 INSR_HUMAN (27-1288): 0: 1183: 52.18		STIM2_HUMAN (49-643): 0: 826: 51.93
+	Hs
		665597 EPHB2_HUMAN (455-1264): 0: 605: 19.86		STIM1_HUMAN (1-685): 0: 1059: 100.00
+	Hs
		665474 EPHA8_HUMAN (454-1268): 2.42e-179: 558: 20.16		STIM1_HUMAN (1-685): 0: 1059: 100.00
+	Hs
		1040300 ALK_HUMAN (946-1247): 1.07e-70: 263: 43.46		STIM1_HUMAN (1-685): 0: 1059: 100.00
+	Hs
		169175 MUSK_HUMAN (973-1242): 8.31e-67: 245: 42.61		STIM1_HUMAN (1-685): 0: 1059: 100.00
+	Hs
		384799 NTRK1_HUMAN (957-1247): 1.28e-65: 240: 42.91		STIM1_HUMAN (1-685): 0: 1059: 100.00
+	Hs
		1040115 NTRK3_HUMAN (957-1242): 2.05e-62: 231: 40.84		STIM1_HUMAN (1-685): 0: 1059: 100.00
+	Hs
		507985 FGFR1_HUMAN (948-1294): 6.81e-59: 221: 35.90		STIM1_HUMAN (1-685): 0: 1059: 100.00
+	Hs
		601912 ERBB3_HUMAN (2-296): 3.16e-34: 145: 18.24		STIM1_HUMAN (1-685): 0: 1059: 100.00
+	Hs
		445849 ROS1_HUMAN (764-900): 8.58e-11: 68.9: 22.63		STIM1_HUMAN (1-685): 0: 1059: 100.00
+	Hs
		1350041 ALK_HUMAN (946-1247): 1.07e-70: 263: 43.46		STIM2_HUMAN (49-643): 0: 826: 51.93
+	Hs
		1081633 NTRK3_HUMAN (957-1242): 2.05e-62: 231: 40.84		STIM2_HUMAN (49-643): 0: 826: 51.93
+	Hs
		508240 FGFR1_HUMAN (948-1294): 6.81e-59: 221: 35.90		STIM2_HUMAN (49-643): 0: 826: 51.93