Protein: IPO11
Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11)

Gene: IPO11
Organism: Homo sapiens
Interactions: 144
UniProt ID: Q9UI26

Gene Ontology (top 5):
GO:0005635 - nuclear envelope
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006606 - protein import into nucleus
GO:0006610 - ribosomal protein import into nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

909407

UB2E1
Ubiquitin-conjugating enzyme E2 E1

2

3

Small-scale

0.793

High

981730

RAN
GTP-binding nuclear protein Ran

2

20

Small-scale

0.793

High

1381216

UB2E3
Ubiquitin-conjugating enzyme E2 E3

1

3

Small-scale

0.680

High

1460207

TN13B
Tumor necrosis factor ligand superfamily member 13B

4

8

High-throughput

0.638

High

774694

BASI
Basigin

4

10

High-throughput

0.633

High

1124317

IF4A2
Eukaryotic initiation factor 4A-II

2

14

High-throughput

0.631

High

262332

SCN2B
Sodium channel regulatory subunit beta-2

4

13

High-throughput

0.630

High

1460206

FZD10
Frizzled-10

2

6

High-throughput

0.628

High

955728

CDC42
Cell division control protein 42 homolog

1

14

High-throughput

0.618

High

962611

RHOA
Transforming protein RhoA

1

16

High-throughput

0.618

High

971252

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

8

High-throughput

0.618

High

1015889

RHOG
Rho-related GTP-binding protein RhoG

1

13

High-throughput

0.618

High

1447694

BIRC6
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6

1

14

High-throughput

0.618

High

608781

DDX5
Probable ATP-dependent RNA helicase DDX5

2

7

High-throughput

0.611

High

1187597

AR13B
ADP-ribosylation factor-like protein 13B

2

6

High-throughput

0.611

High

1291706

CMTD1
Catechol O-methyltransferase domain-containing protein 1

3

8

High-throughput

0.609

High

1031022

K22O
Keratin, type II cytoskeletal 2 oral

2

4

High-throughput

0.606

High

771262

APJ
Apelin receptor

3

10

High-throughput

0.604

High

1330758

SIGL1
SIGLEC family-like protein 1

3

6

High-throughput

0.604

High

363989

EGFR
Epidermal growth factor receptor

2

13

High-throughput

0.584

High

1273132

MOB1B
MOB kinase activator 1B

2

5

High-throughput

0.584

High

1436458

MOB1A
MOB kinase activator 1A

2

5

High-throughput

0.584

High

1397301

UB2E2
Ubiquitin-conjugating enzyme E2 E2

1

3

Small-scale

0.579

High

466986

ACM4
Muscarinic acetylcholine receptor M4

2

11

High-throughput

0.574

High

702864

5HT2C
5-hydroxytryptamine receptor 2C

2

8

High-throughput

0.574

High

749297

CD70
CD70 antigen

2

2

High-throughput

0.574

High

770934

OPRM
Mu-type opioid receptor

2

13

High-throughput

0.574

High

854596

S15A1
Solute carrier family 15 member 1

2

9

High-throughput

0.574

High

1436013

PACC1
Proton-activated chloride channel

2

6

High-throughput

0.574

High

564522

CFTR
Cystic fibrosis transmembrane conductance regulator

2

12

High-throughput

0.571

High

851095

LPAR6
Lysophosphatidic acid receptor 6

2

20

High-throughput

0.558

High

1326239

PNKD
Probable thioesterase PNKD

2

5

High-throughput

0.558

High

1419430

RHBT2
Rho-related BTB domain-containing protein 2

1

17

High-throughput

0.553

High

638547

FPR1
fMet-Leu-Phe receptor

2

16

High-throughput

0.549

High

683363

TNR5
Tumor necrosis factor receptor superfamily member 5

2

10

High-throughput

0.549

High

1101697

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

2

20

High-throughput

0.549

High

1448673

GTR9
Solute carrier family 2, facilitated glucose transporter member 9

2

6

High-throughput

0.549

High

1460211

NPTN
Neuroplastin

2

11

High-throughput

0.549

High

1090966

TRAF2
TNF receptor-associated factor 2

1

3

High-throughput

0.541

High

210430

MTLR
Motilin receptor

1

15

High-throughput

0.536

High

486636

TACD2
Tumor-associated calcium signal transducer 2

1

2

High-throughput

0.536

High

690423

STOM
Stomatin

1

8

High-throughput

0.536

High

1311240

UN45B
Protein unc-45 homolog B

1

16

High-throughput

0.536

High

1429951

BRD8
Bromodomain-containing protein 8

1

13

High-throughput

0.536

High

1241250

CA094
Uncharacterized protein C1orf94

1

1

High-throughput

0.523

High

1411085

PLCD4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4

1

0

High-throughput

0.518

High

1121554

KEAP1
Kelch-like ECH-associated protein 1

1

6

Small-scale

0.501

High

1458757

NXF1
Nuclear RNA export factor 1

1

8

Small-scale

0.501

High

166068

FFAR1
Free fatty acid receptor 1

1

20

High-throughput

0.489

High

182821

GP182
G-protein coupled receptor 182

1

20

High-throughput

0.489

High

209136

CYB5B
Cytochrome b5 type B

1

4

High-throughput

0.489

High

351983

S1PR4
Sphingosine 1-phosphate receptor 4

1

15

High-throughput

0.489

High

592750

LEUK
Leukosialin

1

1

High-throughput

0.489

High

665328

EDNRB
Endothelin receptor type B

1

9

High-throughput

0.489

High

669082

FPR2
N-formyl peptide receptor 2

1

17

High-throughput

0.489

High

711602

NK3R
Neuromedin-K receptor

1

3

High-throughput

0.489

High

719854

V2R
Vasopressin V2 receptor

1

12

High-throughput

0.489

High

733094

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

7

High-throughput

0.489

High

835416

VIPR2
Vasoactive intestinal polypeptide receptor 2

1

7

High-throughput

0.489

High

868026

GLR
Glucagon receptor

1

13

High-throughput

0.489

High

880218

PTH2R
Parathyroid hormone 2 receptor

1

7

High-throughput

0.489

High

907069

CCR6
C-C chemokine receptor type 6

1

13

High-throughput

0.489

High

936136

PAR2
Proteinase-activated receptor 2

1

20

High-throughput

0.489

High

1022985

EFNB1
Ephrin-B1

1

7

High-throughput

0.489

High

1142212

P2RY6
P2Y purinoceptor 6

1

20

High-throughput

0.489

High

1238260

CK087
Uncharacterized protein C11orf87

1

1

High-throughput

0.489

High

1249868

BTNL9
Butyrophilin-like protein 9

1

5

High-throughput

0.489

High

1291918

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

20

High-throughput

0.489

High

1325945

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

5

High-throughput

0.489

High

1381407

MUL1
Mitochondrial ubiquitin ligase activator of NFKB 1

1

7

High-throughput

0.489

High

1399641

OPALI
Opalin

1

3

High-throughput

0.489

High

1430702

F234A
Protein FAM234A

1

7

High-throughput

0.489

High

1431002

UN93B
Protein unc-93 homolog B1

1

8

High-throughput

0.489

High

1447215

GPR84
G-protein coupled receptor 84

1

15

High-throughput

0.489

High

1460205

CC018
Uncharacterized protein C3orf18

1

1

High-throughput

0.489

High

1460210

GPR45
Probable G-protein coupled receptor 45

1

16

High-throughput

0.489

High

716992

RL12
Large ribosomal subunit protein uL11

1

1

Small-scale

0.481

High

129526

MEN1
Menin

1

1

High-throughput

0.479

High

245752

GANP
Germinal-center associated nuclear protein

1

15

High-throughput

0.479

High

291582

NU155
Nuclear pore complex protein Nup155

1

6

High-throughput

0.479

High

326083

UBR5
E3 ubiquitin-protein ligase UBR5

1

11

High-throughput

0.479

High

343098

HERC2
E3 ubiquitin-protein ligase HERC2

1

14

High-throughput

0.479

High

350170

SNAI1
Zinc finger protein SNAI1

1

20

High-throughput

0.479

High

373428

MYC
Myc proto-oncogene protein

1

11

High-throughput

0.479

High

538073

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.479

High

731682

STIP1
Stress-induced-phosphoprotein 1

1

11

High-throughput

0.479

High

766923

PHB1
Prohibitin 1

1

8

Small-scale

0.479

High

845492

PE2R3
Prostaglandin E2 receptor EP3 subtype

1

14

High-throughput

0.479

High

879593

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.479

High

954022

IF4A1
Eukaryotic initiation factor 4A-I

1

15

High-throughput

0.479

High

975300

ARF6
ADP-ribosylation factor 6

1

3

High-throughput

0.479

High

1086344

TFCP2
Alpha-globin transcription factor CP2

1

5

High-throughput

0.479

High

1114587

CUL3
Cullin-3

1

9

High-throughput

0.479

High

1119024

BYST
Bystin

1

2

High-throughput

0.479

High

1178451

CL16A
Protein CLEC16A

1

2

High-throughput

0.479

High

1227656

A16L1
Autophagy-related protein 16-1

1

17

High-throughput

0.479

High

1276177

NUP54
Nucleoporin p54

1

20

High-throughput

0.479

High

1335049

SERB1
SERPINE1 mRNA-binding protein 1

1

7

High-throughput

0.479

High

1338421

FBX22
F-box only protein 22

1

1

High-throughput

0.479

High

1448307

FBX6
F-box only protein 6

1

2

High-throughput

0.479

High

1453026

TLS1
Splicing factor C9orf78

1

6

High-throughput

0.479

High

1459216

ZRAN1
Ubiquitin thioesterase ZRANB1

1

15

High-throughput

0.479

High

171609

S27A2
Long-chain fatty acid transport protein 2

1

20

High-throughput

0.445

High

1209769

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

7

High-throughput

0.445

High

106810

APRIO
Alternative prion protein

1

6

High-throughput

0.437

High

277430

TP4A3
Protein tyrosine phosphatase type IVA 3

1

13

High-throughput

0.437

High

412768

NTRK1
High affinity nerve growth factor receptor

1

11

High-throughput

0.437

High

778109

VGFR2
Vascular endothelial growth factor receptor 2

1

3

High-throughput

0.437

High

787096

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

3

High-throughput

0.437

High

913737

ZN136
Zinc finger protein 136

1

13

High-throughput

0.437

High

1141347

BRD3
Bromodomain-containing protein 3

1

12

High-throughput

0.437

High

1249308

LMBRL
Protein LMBR1L

1

5

High-throughput

0.437

High

1255994

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.437

High

1256628

CE128
Centrosomal protein of 128 kDa

1

6

High-throughput

0.437

High

1271316

5MP2
eIF5-mimic protein 2

1

6

High-throughput

0.437

High

1431472

P2Y12
P2Y purinoceptor 12

1

20

High-throughput

0.437

High

1434170

PKHA4
Pleckstrin homology domain-containing family A member 4

1

19

High-throughput

0.437

High

1460208

AAR2
Protein AAR2 homolog

1

3

High-throughput

0.437

High

1460212

5MP1
eIF5-mimic protein 1

1

6

High-throughput

0.437

High

248958

GSDME
Gasdermin-E

1

0

High-throughput

0.426

High

887307

CEBPA
CCAAT/enhancer-binding protein alpha

1

9

High-throughput

0.408

High

1155

SIM26
Small integral membrane protein 26

1

6

High-throughput

0.407

High

50728

HACL2
2-hydroxyacyl-CoA lyase 2

1

1

High-throughput

0.407

High

166444

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

3

High-throughput

0.407

High

190268

MOT4
Monocarboxylate transporter 4

1

8

High-throughput

0.407

High

704090

5HT1E
5-hydroxytryptamine receptor 1E

1

9

High-throughput

0.407

High

754119

CD80
T-lymphocyte activation antigen CD80

1

20

High-throughput

0.407

High

886151

CXCR3
C-X-C chemokine receptor type 3

1

11

High-throughput

0.407

High

1240983

S27A4
Long-chain fatty acid transport protein 4

1

20

High-throughput

0.407

High

1243677

S27A1
Long-chain fatty acid transport protein 1

1

20

High-throughput

0.407

High

1280825

S35E3
Solute carrier family 35 member E3

1

5

High-throughput

0.407

High

1350792

MO2R1
Cell surface glycoprotein CD200 receptor 1

1

2

High-throughput

0.407

High

1366297

LPAR1
Lysophosphatidic acid receptor 1

1

15

High-throughput

0.407

High

1391471

S35A4
Probable UDP-sugar transporter protein SLC35A4

1

4

High-throughput

0.407

High

1395677

S35E1
Solute carrier family 35 member E1

1

2

High-throughput

0.407

High

1436665

ZDH11
Palmitoyltransferase ZDHHC11

1

4

High-throughput

0.407

High

1128969

I13R2
Interleukin-13 receptor subunit alpha-2

2

0

High-throughput

0.328

High

139339

UPK2
Uroplakin-2

1

0

High-throughput

0.279

Low

1393904

DHTK1
2-oxoadipate dehydrogenase complex component E1

1

0

High-throughput

0.279

Low

1446719

TMM9B
Transmembrane protein 9B

1

0

High-throughput

0.279

Low

1449096

RPRM
Protein reprimo

1

0

High-throughput

0.279

Low

1414746

RCAF1
GEL complex subunit OPTI

1

0

High-throughput

0.269

Low

1460209

PHLA3
Pleckstrin homology-like domain family A member 3

1

0

High-throughput

0.249

Low

1446082

S39A2
Zinc transporter ZIP2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025