HitPredict

Interactor 1: ENPL (P14625)
Endoplasmin (94 kDa glucose-regulated protein) (GRP-94) (Heat shock protein 90 kDa beta member 1) (Heat shock protein family C member 4) (Tumor rejection antigen 1) (gp96 homolog)
Gene: HSP90B1

Interactor 2: STIP1 (P31948)
Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Renal carcinoma antigen NY-REN-11) (Transformation-sensitive protein IEF SSP 3521)
Gene: STIP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33239621
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HSP90~TPR_8
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 803 Hs			1 543
+	Hs
		437930 HS90B_HUMAN (75-783): 0: 997: 46.54		STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00
+	Hs
		111934 K9JA46_HUMAN (60-783): 0: 990: 45.34		STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00
+	Hs
		431574 HS90A_HUMAN (60-783): 0: 990: 45.34		STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00
+	At
		878278 HS902_ARATH (71-783): 0: 956: 50.07		HSOP2_ARATH (3-543): 4.73e-97: 307: 41.86
+	Dm
		365481 HSP83_DROME (69-783): 0: 981: 45.74		Q9VPN5_DROME (1-542): 1.4e-79: 259: 47.42
+	Hs
		538353 ENPL_HUMAN (1-803): 0: 1073: 100.00		SGTB_HUMAN (213-348): 5.73e-32: 126: 31.39
+	Hs
		174598 ENPL_HUMAN (1-803): 0: 1073: 100.00		OGT1_HUMAN (5-261): 5.16e-18: 90: 13.57
+	Hs
		438464 HS90B_HUMAN (75-783): 0: 997: 46.54		DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28
+	Hs
		432195 HS90A_HUMAN (60-783): 0: 990: 45.34		DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28
+	Hs
		438533 HS90B_HUMAN (75-783): 0: 997: 46.54		RPAP3_HUMAN (2-141): 4.46e-20: 96.1: 27.14
+	Hs
		174561 HS90B_HUMAN (75-783): 0: 997: 46.54		OGT1_HUMAN (5-261): 5.16e-18: 90: 13.57
+	Hs
		432268 HS90A_HUMAN (60-783): 0: 990: 45.34		RPAP3_HUMAN (2-141): 4.46e-20: 96.1: 27.14
+	Hs
		174556 HS90A_HUMAN (60-783): 0: 990: 45.34		OGT1_HUMAN (5-261): 5.16e-18: 90: 13.57
+	Hs
		297025 HS90B_HUMAN (75-783): 0: 997: 46.54		TOM70_HUMAN (207-543): 4.08e-13: 73.8: 11.00
+	Hs
		297024 HS90A_HUMAN (60-783): 0: 990: 45.34		TOM70_HUMAN (207-543): 4.08e-13: 73.8: 11.00
+	Hs
		431774 HS90A_HUMAN (60-783): 0: 990: 45.34		SPAG1_HUMAN (405-527): 2.93e-11: 68.4: 14.63
+	Hs
		213454 HS90B_HUMAN (75-783): 0: 997: 46.54		SGTA_HUMAN (202-327): 3.98e-09: 60.1: 32.54
+	Hs
		431797 HS90A_HUMAN (60-783): 0: 990: 45.34		IFT88_HUMAN (4-150): 8.37e-09: 60.3: 12.93
+	Hs
		213451 HS90A_HUMAN (60-783): 0: 990: 45.34		SGTA_HUMAN (202-327): 3.98e-09: 60.1: 32.54
+	Ce
		183711 HSP90_CAEEL (69-783): 0: 924: 46.79		STIP1_CAEEL (2-280): 5.87e-13: 71.9: 13.24