Protein: CP3A4
Cytochrome P450 3A4 (EC 1.14.14.1) (1,4-cineole 2-exo-monooxygenase) (1,8-cineole 2-exo-monooxygenase) (EC 1.14.14.56) (Albendazole monooxygenase (sulfoxide-forming)) (EC 1.14.14.73) (Albendazole sulfoxidase) (CYPIIIA3) (CYPIIIA4) (Cholesterol 25-hydroxylase) (Cytochrome P450 3A3) (Cytochrome P450 HLp) (Cytochrome P450 NF-25) (Cytochrome P450-PCN1) (Nifedipine oxidase) (Quinine 3-monooxygenase) (EC 1.14.14.55)

Gene: CP3A4, CYP3A4
Organism: Homo sapiens
Interactions: 21
UniProt ID: P08684

Gene Ontology (top 5):
GO:0002933 - lipid hydroxylation
GO:0004497 - monooxygenase activity
GO:0005496 - steroid binding
GO:0005506 - iron ion binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

475195

AMFR
E3 ubiquitin-protein ligase AMFR

4

1

Small-scale

0.698

High

475184

UD2B7
UDP-glucuronosyltransferase 2B7

4

3

Small-scale

0.689

High

475196

CHIP
E3 ubiquitin-protein ligase CHIP

3

3

Small-scale

0.670

High

475189

CP3A5
Cytochrome P450 3A5

1

13

High-throughput

0.665

High

475182

CP2C9
Cytochrome P450 2C9

1

11

Small-scale

0.647

High

475183

NCPR
NADPH--cytochrome P450 reductase

1

4

Small-scale

0.647

High

475180

CP3A4
Cytochrome P450 3A4

1

11

Small-scale

0.618

High

129962

PGRC1
Membrane-associated progesterone receptor component 1

1

7

Small-scale

0.515

High

357903

CYB5
Cytochrome b5

1

4

Small-scale

0.501

High

475186

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

1

Small-scale

0.501

High

475194

LIAT1
Protein LIAT1

1

0

High-throughput

0.493

High

475185

KPCA
Protein kinase C alpha type

1

0

Small-scale

0.480

High

475181

HSP7C
Heat shock cognate 71 kDa protein

1

1

Small-scale

0.479

High

475187

CEBPB
CCAAT/enhancer-binding protein beta

1

1

Small-scale

0.479

High

475188

UD16
UDP-glucuronosyltransferase 1A6

1

3

Small-scale

0.479

High

475190

UD11
UDP-glucuronosyltransferase 1A1

1

3

Small-scale

0.479

High

475192

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

1

Small-scale

0.479

High

185145

FANCG
Fanconi anemia group G protein

1

1

High-throughput

0.470

High

475193

UB2G1
Ubiquitin-conjugating enzyme E2 G1

1

2

Small-scale

0.437

High

475191

GLPK
Glycerol kinase

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025