HitPredict

Interactor 1: HXB2 (P14652)
Homeobox protein Hox-B2 (Homeobox protein Hox-2.8) (Homeobox protein Hox-2H) (K8)
Gene: HOXB2

Interactor 2: TNKS2 (Q9H2K2)
Poly [ADP-ribose] polymerase tankyrase-2 (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 6) (ARTD6) (Poly [ADP-ribose] polymerase 5B) (Protein poly-ADP-ribosyltransferase tankyrase-2) (EC 2.4.2.-) (TNKS-2) (TRF1-interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase II) (Tankyrase-2) (TANK2) (Tankyrase-like protein) (Tankyrase-related protein)
Gene: TNKS2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.50	0.600

Property	Details
Experiments	35016035, 12080061, 22153077
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid, fluorescence polarization spectroscopy
Interaction Type	physical association, association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 356 Hs			1 1166
+	Hs
		310033 HXB2_HUMAN (1-356): 1.23e-62: 205: 100.00		TNKS1_HUMAN (2-335): 1.11e-73: 270: 35.95
+	Hs
		166877 HXC4_HUMAN (56-254): 2.27e-38: 139: 31.66		ANR28_HUMAN (7-525): 2.62e-78: 281: 22.10
+	Hs
		166890 HXA7_HUMAN (44-214): 7.2e-31: 118: 26.71		ANR28_HUMAN (7-525): 2.62e-78: 281: 22.10
+	Hs
		595612 HXA5_HUMAN (35-213): 1.32e-41: 148: 31.87		ANKH1_HUMAN (2-117): 5.71e-23: 108: 26.72
+	Hs
		958874 HXA4_HUMAN (67-248): 1.47e-38: 141: 33.52		ANKH1_HUMAN (2-117): 5.71e-23: 108: 26.72
+	Hs
		257562 HXA5_HUMAN (35-213): 1.32e-41: 148: 31.87		ANR17_HUMAN (809-1134): 3.89e-20: 99.4: 8.98
+	Hs
		446906 HXC4_HUMAN (56-254): 2.27e-38: 139: 31.66		ANKH1_HUMAN (2-117): 5.71e-23: 108: 26.72
+	Hs
		257599 HXA4_HUMAN (67-248): 1.47e-38: 141: 33.52		ANR17_HUMAN (809-1134): 3.89e-20: 99.4: 8.98
+	Hs
		257550 HXC4_HUMAN (56-254): 2.27e-38: 139: 31.66		ANR17_HUMAN (809-1134): 3.89e-20: 99.4: 8.98
+	Hs
		453058 HXB7_HUMAN (1-212): 9.77e-34: 125: 25.94		ANKH1_HUMAN (2-117): 5.71e-23: 108: 26.72
+	Hs
		567802 HXB8_HUMAN (32-229): 1.43e-32: 123: 25.49		ANKH1_HUMAN (2-117): 5.71e-23: 108: 26.72
+	Hs
		446872 HXD4_HUMAN (4-232): 9.13e-31: 119: 30.74		ANKH1_HUMAN (2-117): 5.71e-23: 108: 26.72
+	Hs
		678842 HXA7_HUMAN (44-214): 7.2e-31: 118: 26.71		ANKH1_HUMAN (2-117): 5.71e-23: 108: 26.72
+	Hs
		92414 HXC4_HUMAN (56-254): 2.27e-38: 139: 31.66		E9PDP5_HUMAN (770-1134): 4.35e-16: 86: 9.46
+	Hs
		257551 HXB7_HUMAN (1-212): 9.77e-34: 125: 25.94		ANR17_HUMAN (809-1134): 3.89e-20: 99.4: 8.98
+	Hs
		257549 HXD4_HUMAN (4-232): 9.13e-31: 119: 30.74		ANR17_HUMAN (809-1134): 3.89e-20: 99.4: 8.98
+	Hs
		257570 HXA7_HUMAN (44-214): 7.2e-31: 118: 26.71		ANR17_HUMAN (809-1134): 3.89e-20: 99.4: 8.98