Protein: GTR5
Solute carrier family 2, facilitated glucose transporter member 5 (Fructose transporter) (Glucose transporter type 5, small intestine) (GLUT-5)

Gene: GTR5, SLC2A5
Organism: Homo sapiens
Interactions: 135
UniProt ID: P22732

Gene Ontology (top 5):
GO:0003044 - regulation of systemic arterial blood pressure mediated by a chemical signal
GO:0005353 - fructose transmembrane transporter activity
GO:0005886 - plasma membrane
GO:0005975 - carbohydrate metabolic process
GO:0009750 - response to fructose

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

652262

SCN3B
Sodium channel regulatory subunit beta-3

2

1

High-throughput

0.783

High

652202

LMBD2
G-protein coupled receptor-associated protein LMBRD2

3

1

High-throughput

0.662

High

652179

AT12A
Potassium-transporting ATPase alpha chain 2

2

7

High-throughput

0.628

High

652184

AT2B2
Plasma membrane calcium-transporting ATPase 2

2

11

High-throughput

0.628

High

652220

CTR3
Cationic amino acid transporter 3

2

8

High-throughput

0.628

High

652238

VATO
V-type proton ATPase 21 kDa proteolipid subunit c''

2

1

High-throughput

0.606

High

652246

OSBL6
Oxysterol-binding protein-related protein 6

2

0

High-throughput

0.602

High

652194

AR13B
ADP-ribosylation factor-like protein 13B

3

15

High-throughput

0.591

High

642192

COMT
Catechol O-methyltransferase

2

0

High-throughput

0.580

High

652177

EVI2B
Protein EVI2B

2

0

High-throughput

0.580

High

652216

TM130
Transmembrane protein 130

2

0

High-throughput

0.580

High

652235

TM237
Transmembrane protein 237

2

0

High-throughput

0.580

High

65298

RFOX3
RNA binding protein fox-1 homolog 3

2

1

High-throughput

0.574

High

166862

MGST3
Glutathione S-transferase 3, mitochondrial

2

1

High-throughput

0.553

High

652234

FCRL3
Fc receptor-like protein 3

2

2

High-throughput

0.553

High

652222

LGAT1
Acyl-CoA:lysophosphatidylglycerol acyltransferase 1

2

3

High-throughput

0.549

High

476558

RSSA
Small ribosomal subunit protein uS2

1

3

High-throughput

0.541

High

296653

AL1L1
Cytosolic 10-formyltetrahydrofolate dehydrogenase

1

5

High-throughput

0.536

High

295801

FACE1
CAAX prenyl protease 1 homolog

1

0

High-throughput

0.513

High

652201

ECM29
Proteasome adapter and scaffold protein ECM29

1

7

High-throughput

0.489

High

48526

ESYT2
Extended synaptotagmin-2

1

8

High-throughput

0.445

High

249424

ACSL4
Long-chain-fatty-acid--CoA ligase 4

1

3

High-throughput

0.445

High

350215

FADS2
Acyl-CoA 6-desaturase

1

2

High-throughput

0.445

High

403127

APOB
Apolipoprotein B-100

1

2

High-throughput

0.445

High

420767

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

4

High-throughput

0.445

High

421510

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.445

High

443182

CDK1
Cyclin-dependent kinase 1

1

1

High-throughput

0.445

High

652176

AT2B4
Plasma membrane calcium-transporting ATPase 4

1

10

High-throughput

0.445

High

652178

GALK1
Galactokinase

1

1

High-throughput

0.445

High

652180

XPO2
Exportin-2

1

4

High-throughput

0.445

High

652181

PSA
Puromycin-sensitive aminopeptidase

1

3

High-throughput

0.445

High

652183

AT2C1
Calcium-transporting ATPase type 2C member 1

1

9

High-throughput

0.445

High

652189

RB39A
Ras-related protein Rab-39A

1

13

High-throughput

0.445

High

652192

OCLN
Occludin

1

2

High-throughput

0.445

High

652207

MON2
Protein MON2 homolog

1

6

High-throughput

0.445

High

652210

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

7

High-throughput

0.445

High

652229

COQ8B
Atypical kinase COQ8B, mitochondrial

1

3

High-throughput

0.445

High

652231

ABHEB
Putative protein-lysine deacylase ABHD14B

1

1

High-throughput

0.445

High

652239

SORT
Sortilin

1

2

High-throughput

0.445

High

652240

CAB45
45 kDa calcium-binding protein

1

2

High-throughput

0.445

High

652242

ESYT1
Extended synaptotagmin-1

1

8

High-throughput

0.445

High

652244

TMM43
Transmembrane protein 43

1

3

High-throughput

0.445

High

652261

MIC19
MICOS complex subunit MIC19

1

3

High-throughput

0.445

High

652264

VATH
V-type proton ATPase subunit H

1

2

High-throughput

0.445

High

652267

VPS4A
Vacuolar protein sorting-associated protein 4A

1

1

High-throughput

0.445

High

652268

PLAP
Phospholipase A-2-activating protein

1

2

High-throughput

0.445

High

652272

RN114
E3 ubiquitin-protein ligase RNF114

1

1

High-throughput

0.445

High

652275

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

1

High-throughput

0.445

High

385461

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

4

High-throughput

0.439

High

652259

UBP40
Ubiquitin carboxyl-terminal hydrolase 40

1

1

Small-scale

0.439

High

652185

CAV1
Caveolin-1

1

0

High-throughput

0.426

High

652200

SNP47
Synaptosomal-associated protein 47

1

0

High-throughput

0.426

High

652212

PLPP6
Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6

1

0

High-throughput

0.426

High

652260

AIG1
Androgen-induced gene 1 protein

1

0

High-throughput

0.426

High

85335

GPHRA
Golgi pH regulator A

1

1

High-throughput

0.407

High

161188

EI24
Etoposide-induced protein 2.4 homolog

1

1

High-throughput

0.407

High

172475

XPO1
Exportin-1

1

5

High-throughput

0.407

High

173656

BTAF1
TATA-binding protein-associated factor 172

1

2

High-throughput

0.407

High

184803

SPTC1
Serine palmitoyltransferase 1

1

1

High-throughput

0.407

High

184964

SPTC2
Serine palmitoyltransferase 2

1

1

High-throughput

0.407

High

186404

TM9S1
Transmembrane 9 superfamily member 1

1

4

High-throughput

0.407

High

228062

PM34
Peroxisomal membrane protein PMP34

1

4

High-throughput

0.407

High

280125

SC22B
Vesicle-trafficking protein SEC22b

1

4

High-throughput

0.407

High

302752

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

3

High-throughput

0.407

High

539031

UMPS
Uridine 5'-monophosphate synthase

1

1

High-throughput

0.407

High

592990

ACADS
Short-chain specific acyl-CoA dehydrogenase, mitochondrial

1

4

High-throughput

0.407

High

621434

HXK1
Hexokinase-1

1

2

High-throughput

0.407

High

651746

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

3

High-throughput

0.407

High

652182

PEX3
Peroxisomal biogenesis factor 3

1

2

High-throughput

0.407

High

652186

TAP1
Antigen peptide transporter 1

1

5

High-throughput

0.407

High

652187

TM115
Transmembrane protein 115

1

1

High-throughput

0.407

High

652188

MTX1
Metaxin-1

1

2

High-throughput

0.407

High

652191

DHC24
Delta(24)-sterol reductase

1

2

High-throughput

0.407

High

652193

MIC60
MICOS complex subunit MIC60

1

2

High-throughput

0.407

High

652196

YIF1B
Protein YIF1B

1

2

High-throughput

0.407

High

652197

RABL3
Rab-like protein 3

1

13

High-throughput

0.407

High

652198

COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

1

2

High-throughput

0.407

High

652199

SYEM
Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial

1

1

High-throughput

0.407

High

652203

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

1

2

High-throughput

0.407

High

652205

NFXL1
NF-X1-type zinc finger protein NFXL1

1

1

High-throughput

0.407

High

652206

HS2ST
Heparan sulfate 2-O-sulfotransferase 1

1

1

High-throughput

0.407

High

652208

PIGW
Glucosaminyl-phosphatidylinositol-acyltransferase PIGW

1

2

High-throughput

0.407

High

652209

GPAT4
Glycerol-3-phosphate acyltransferase 4

1

5

High-throughput

0.407

High

652211

VRK2
Serine/threonine-protein kinase VRK2

1

3

High-throughput

0.407

High

652214

VKORL
Vitamin K epoxide reductase complex subunit 1-like protein 1

1

1

High-throughput

0.407

High

652218

COQ8A
Atypical kinase COQ8A, mitochondrial

1

3

High-throughput

0.407

High

652223

GCN1
Stalled ribosome sensor GCN1

1

8

High-throughput

0.407

High

652224

NU205
Nuclear pore complex protein Nup205

1

2

High-throughput

0.407

High

652225

GCDH
Glutaryl-CoA dehydrogenase, mitochondrial

1

4

High-throughput

0.407

High

652226

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

4

High-throughput

0.407

High

652228

CCD47
PAT complex subunit CCDC47

1

1

High-throughput

0.407

High

652236

TM209
Transmembrane protein 209

1

1

High-throughput

0.407

High

652241

GCP2
Gamma-tubulin complex component 2

1

1

High-throughput

0.407

High

652249

DERL2
Derlin-2

1

1

High-throughput

0.407

High

652251

XPO5
Exportin-5

1

8

High-throughput

0.407

High

652252

S38AA
Solute carrier family 38 member 10

1

3

High-throughput

0.407

High

652253

TM9S3
Transmembrane 9 superfamily member 3

1

4

High-throughput

0.407

High

652254

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

1

High-throughput

0.407

High

652255

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

1

High-throughput

0.407

High

652257

ECHD1
Ethylmalonyl-CoA decarboxylase

1

2

High-throughput

0.407

High

652258

DECR2
Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]

1

4

High-throughput

0.407

High

652265

MA1B1
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

1

1

High-throughput

0.407

High

652269

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

4

High-throughput

0.407

High

652270

C2CD2
C2 domain-containing protein 2

1

1

High-throughput

0.407

High

652271

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

2

High-throughput

0.407

High

652273

FADS3
Fatty acid desaturase 3

1

2

High-throughput

0.407

High

652217

FITM2
Acyl-coenzyme A diphosphatase FITM2

2

0

High-throughput

0.328

High

282515

PAGE1
P antigen family member 1

2

0

High-throughput

0.316

High

652230

MTEF3
Transcription termination factor 3, mitochondrial

2

0

High-throughput

0.316

High

562868

CCL5
C-C motif chemokine 5

1

0

High-throughput

0.282

High

652248

FTO
Alpha-ketoglutarate-dependent dioxygenase FTO

1

0

High-throughput

0.279

Low

50492

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.232

Low

122591

UBXN8
UBX domain-containing protein 8

1

0

High-throughput

0.232

Low

128384

PSMD9
26S proteasome non-ATPase regulatory subunit 9

1

0

High-throughput

0.232

Low

144404

SCD
Stearoyl-CoA desaturase

1

0

High-throughput

0.232

Low

431386

AT5G1
ATP synthase F(0) complex subunit C1, mitochondrial

1

0

High-throughput

0.232

Low

652190

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

1

0

High-throughput

0.232

Low

652195

TM177
Transmembrane protein 177

1

0

High-throughput

0.232

Low

652204

TMT1B
Thiol S-methyltransferase TMT1B

1

0

High-throughput

0.232

Low

652213

K2013
Uncharacterized protein KIAA2013

1

0

High-throughput

0.232

Low

652215

NUP93
Nuclear pore complex protein Nup93

1

0

High-throughput

0.232

Low

652219

PIGX
GPI alpha-1,4-mannosyltransferase I, stabilizing subunit

1

0

High-throughput

0.232

Low

652221

PMGT1
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

1

0

High-throughput

0.232

Low

652227

F162A
Protein FAM162A

1

0

High-throughput

0.232

Low

652232

S35E1
Solute carrier family 35 member E1

1

0

High-throughput

0.232

Low

652233

SMIM8
Small integral membrane protein 8

1

0

High-throughput

0.232

Low

652237

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.232

Low

652243

ALG1
Chitobiosyldiphosphodolichol beta-mannosyltransferase

1

0

High-throughput

0.232

Low

652245

THTPA
Thiamine-triphosphatase

1

0

High-throughput

0.232

Low

652247

UCK2
Uridine-cytidine kinase 2

1

0

High-throughput

0.232

Low

652250

UN45A
Protein unc-45 homolog A

1

0

High-throughput

0.232

Low

652256

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.232

Low

652263

AASS
Alpha-aminoadipic semialdehyde synthase, mitochondrial

1

0

High-throughput

0.232

Low

652266

TMCC3
Transmembrane and coiled-coil domain protein 3

1

0

High-throughput

0.232

Low

652274

UBIA1
UbiA prenyltransferase domain-containing protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025