HitPredict

Interactor 1: KSS1 (P14681)
Mitogen-activated protein kinase KSS1 (MAP kinase KSS1) (EC 2.7.11.24) (Kinase suppressor of SST2)
Gene: KSS1

Interactor 2: BEM3 (P32873)
GTPase-activating protein BEM3 (Bud emergence protein 3)
Gene: BEM3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.857

Property	Details
Experiments	11805837, 28064039, 21118957
Identification Methods	anti tag coimmunoprecipitation, two hybrid, protein complementation assay, affinity chromatography technology
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	PH~Pkinase
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 368 Sc			1 1128
+	Hs
		551039 MK01_HUMAN (1-367): 2.23e-136: 394: 48.77		CHIN_HUMAN (802-1122): 3.19e-71: 247: 19.94
+	Hs
		659018 MK01_HUMAN (1-367): 2.23e-136: 394: 48.77		HMHA1_HUMAN (665-1125): 2.59e-61: 230: 13.80
+	Hs
		960119 CDK3_HUMAN (10-328): 1.52e-131: 380: 36.88		RGAP1_HUMAN (647-1128): 1e-65: 236: 16.80
+	Hs
		647661 MK03_HUMAN (1-367): 2.13e-137: 397: 46.87		RHG07_HUMAN (774-1090): 7.02e-52: 202: 17.43
+	Hs
		659037 MK01_HUMAN (1-367): 2.23e-136: 394: 48.77		RHG09_HUMAN (900-1092): 1.88e-36: 150: 28.43
+	Hs
		1082624 MK14_HUMAN (7-364): 1.09e-98: 298: 45.00		RHG09_HUMAN (900-1092): 1.88e-36: 150: 28.43