HitPredict

Interactor 1: LMNB1 (P14733)
Lamin-B1
Gene: LMNB1

Interactor 2: SOX2 (P48432)
Transcription factor SOX-2
Gene: SOX2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31077711
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 588 Mm			1 319
+	Hs
		531540 K2C5_HUMAN (26-392): 1.21e-123: 378: 23.51		SOX2_HUMAN (1-319): 2.01e-64: 207: 94.67
+	Hs
		595134 LMNB1_HUMAN (21-588): 4.74e-56: 200: 96.83		SOX2_HUMAN (1-319): 2.01e-64: 207: 94.67
+	Hs
		817952 LMNB2_HUMAN (21-588): 6.27e-50: 184: 56.05		SOX2_HUMAN (1-319): 2.01e-64: 207: 94.67
+	Hs
		595369 LMNB1_HUMAN (21-588): 4.74e-56: 200: 96.83		CIC_HUMAN (10-274): 4.32e-43: 160: 23.83
+	Hs
		360312 LMNA_HUMAN (4-582): 1.93e-54: 197: 54.31		CIC_HUMAN (10-274): 4.32e-43: 160: 23.83
+	Hs
		975718 LMNB2_HUMAN (21-588): 6.27e-50: 184: 56.05		CIC_HUMAN (10-274): 4.32e-43: 160: 23.83
+	Hs
		360221 LMNA_HUMAN (4-582): 1.93e-54: 197: 54.31		BBX_HUMAN (31-255): 1.96e-35: 137: 19.13
+	Mm
		589617 VIME_MOUSE (29-391): 2.49e-29: 123: 28.38		SOX2_MOUSE (1-319): 3.85e-64: 207: 100.00
+	Hs
		359880 LMNA_HUMAN (4-582): 1.93e-54: 197: 54.31		SSRP1_HUMAN (21-205): 1.2e-33: 132: 15.14
+	Hs
		331683 LMNA_HUMAN (4-582): 1.93e-54: 197: 54.31		NSD2_HUMAN (1-288): 5.77e-29: 119: 11.04
+	Hs
		975642 LMNB2_HUMAN (21-588): 6.27e-50: 184: 56.05		SOX4_HUMAN (3-291): 7.9e-28: 114: 25.08
+	Hs
		443743 VIME_HUMAN (29-391): 8.02e-30: 124: 28.65		CIC_HUMAN (10-274): 4.32e-43: 160: 23.83
+	Hs
		359638 LMNA_HUMAN (4-582): 1.93e-54: 197: 54.31		UBF1_HUMAN (1-132): 8.57e-13: 70.9: 20.00
+	Hs
		443852 VIME_HUMAN (29-391): 8.02e-30: 124: 28.65		HM20B_HUMAN (11-248): 1.2e-29: 116: 15.00
+	Hs
		1205250 K2C73_HUMAN (261-577): 4.43e-11: 67.6: 7.93		CIC_HUMAN (10-274): 4.32e-43: 160: 23.83
+	Hs
		281074 KRT38_HUMAN (32-408): 2.31e-25: 111: 27.18		HM20B_HUMAN (11-248): 1.2e-29: 116: 15.00
+	Hs
		443313 VIME_HUMAN (29-391): 8.02e-30: 124: 28.65		UBF1_HUMAN (1-132): 8.57e-13: 70.9: 20.00