Protein: UBAC2
Ubiquitin-associated domain-containing protein 2 (UBA domain-containing protein 2) (Phosphoglycerate dehydrogenase-like protein 1)

Gene: UBAC2
Organism: Homo sapiens
Interactions: 203
UniProt ID: Q8NBM4

Gene Ontology (top 5):
GO:0004252 - serine-type endopeptidase activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0016055 - Wnt signaling pathway
GO:0070972 - protein localization to endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

508286

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

5

3

Small-scale

0.919

High

1333684

FAF2
FAS-associated factor 2

7

1

Small-scale

0.744

High

507282

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

3

High-throughput

0.691

High

1333722

AMFR
E3 ubiquitin-protein ligase AMFR

4

1

Small-scale

0.686

High

242299

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.665

High

934866

TERA
Transitional endoplasmic reticulum ATPase

3

1

Small-scale

0.656

High

1333675

TBC15
TBC1 domain family member 15

4

1

High-throughput

0.636

High

1333687

RN185
E3 ubiquitin-protein ligase RNF185

2

1

Small-scale

0.611

High

876933

KC1A
Casein kinase I isoform alpha

1

0

High-throughput

0.586

High

892120

KLK7
Kallikrein-7

2

0

High-throughput

0.585

High

316621

ST17B
Serine/threonine-protein kinase 17B

1

0

High-throughput

0.578

High

1126324

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

2

0

High-throughput

0.576

High

1333708

TBC17
TBC1 domain family member 17

2

1

High-throughput

0.574

High

1333717

ZRAN1
Ubiquitin thioesterase ZRANB1

2

0

High-throughput

0.559

High

1333685

S10AG
Protein S100-A16

2

1

High-throughput

0.558

High

168551

UB2L6
Ubiquitin/ISG15-conjugating enzyme E2 L6

1

1

High-throughput

0.553

High

283308

ERLN1
Erlin-1

1

1

High-throughput

0.536

High

321308

ERLN2
Erlin-2

1

2

High-throughput

0.536

High

595079

KCNA2
Potassium voltage-gated channel subfamily A member 2

1

1

High-throughput

0.536

High

784832

ACHA7
Neuronal acetylcholine receptor subunit alpha-7

1

2

High-throughput

0.536

High

1095715

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

1

High-throughput

0.523

High

184478

SURF4
Surfeit locus protein 4

1

0

High-throughput

0.513

High

280264

SC22B
Vesicle-trafficking protein SEC22b

1

0

High-throughput

0.513

High

292694

RENR
Renin receptor

1

0

High-throughput

0.513

High

418274

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.513

High

547329

CP19A
Aromatase

1

0

High-throughput

0.513

High

564071

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.513

High

578684

GLNA
Glutamine synthetase

1

0

High-throughput

0.513

High

693849

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.513

High

894905

EMD
Emerin

1

0

High-throughput

0.513

High

1030671

ANK2
Ankyrin-2

1

0

High-throughput

0.513

High

1136276

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.513

High

1203729

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.513

High

1276222

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.513

High

1330310

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.513

High

1333676

SPP
Signal peptide peptidase

1

0

High-throughput

0.513

High

1333683

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.513

High

1333691

KCNKG
Potassium channel subfamily K member 16

1

0

High-throughput

0.513

High

1333695

TMM43
Transmembrane protein 43

1

0

High-throughput

0.513

High

1333698

TMED9
Transmembrane emp24 domain-containing protein 9

1

0

High-throughput

0.513

High

1333714

EMC3
ER membrane protein complex subunit 3

1

0

High-throughput

0.513

High

1333715

VAPA
Vesicle-associated membrane protein-associated protein A

1

0

High-throughput

0.513

High

1333727

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.513

High

301572

WFS1
Wolframin

1

0

High-throughput

0.493

High

50115

S22AN
Solute carrier family 22 member 23

1

3

High-throughput

0.489

High

182665

GP182
G-protein coupled receptor 182

1

1

High-throughput

0.489

High

354363

TOM40
Mitochondrial import receptor subunit TOM40 homolog

1

1

High-throughput

0.489

High

388139

ACHA
Acetylcholine receptor subunit alpha

1

2

High-throughput

0.489

High

640958

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

1

High-throughput

0.489

High

720587

AA1R
Adenosine receptor A1

1

1

High-throughput

0.489

High

771176

APJ
Apelin receptor

1

1

High-throughput

0.489

High

967323

TSN5
Tetraspanin-5

1

1

High-throughput

0.489

High

1043862

KCNC4
Voltage-gated potassium channel KCNC4

1

1

High-throughput

0.489

High

1259356

TBA1A
Tubulin alpha-1A chain

1

1

High-throughput

0.489

High

1286340

S1A7A
Protein S100-A7A

1

1

High-throughput

0.489

High

1291070

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

1

High-throughput

0.489

High

1308900

S22A9
Organic anion transporter 7

1

3

High-throughput

0.489

High

1333679

GCN1
Stalled ribosome sensor GCN1

1

1

High-throughput

0.489

High

1333686

TSN17
Tetraspanin-17

1

1

High-throughput

0.489

High

1333693

CML1
Chemerin-like receptor 1

1

1

High-throughput

0.489

High

1333711

TBA8
Tubulin alpha-8 chain

1

1

High-throughput

0.489

High

173997

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

1

High-throughput

0.479

High

178336

NPC1
NPC intracellular cholesterol transporter 1

1

1

High-throughput

0.479

High

466359

RHOC
Rho-related GTP-binding protein RhoC

1

3

High-throughput

0.479

High

786177

LONM
Lon protease homolog, mitochondrial

1

2

High-throughput

0.479

High

955380

CDC42
Cell division control protein 42 homolog

1

5

High-throughput

0.479

High

962274

RHOA
Transforming protein RhoA

1

3

High-throughput

0.479

High

1015604

RHOG
Rho-related GTP-binding protein RhoG

1

3

High-throughput

0.479

High

1287378

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

2

Small-scale

0.479

High

951762

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

1

High-throughput

0.470

High

1333726

RNF11
RING finger protein 11

1

2

High-throughput

0.470

High

414230

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

417589

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

941935

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.458

High

1027088

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.458

High

1043222

TAP2
Antigen peptide transporter 2

1

0

Small-scale

0.458

High

1162427

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.458

High

1249025

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1252894

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.458

High

1309850

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.458

High

1333673

NPL4
Nuclear protein localization protein 4 homolog

1

0

High-throughput

0.458

High

1333689

PANX1
Pannexin-1

1

0

High-throughput

0.458

High

1333697

DERL1
Derlin-1

1

0

High-throughput

0.458

High

565668

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

1

High-throughput

0.445

High

1333674

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

2

High-throughput

0.445

High

1333681

S35B4
Nucleotide sugar transporter SLC35B4

1

2

High-throughput

0.445

High

1333701

S35B3
Adenosine 3'-phospho 5'-phosphosulfate transporter 2

1

2

High-throughput

0.445

High

143122

NFIB
Nuclear factor 1 B-type

1

2

High-throughput

0.437

High

474130

NFIC
Nuclear factor 1 C-type

1

2

High-throughput

0.437

High

783336

TRI23
E3 ubiquitin-protein ligase TRIM23

1

1

High-throughput

0.437

High

939945

TPTE
Putative tyrosine-protein phosphatase TPTE

1

1

High-throughput

0.437

High

1087871

NFIA
Nuclear factor 1 A-type

1

2

High-throughput

0.437

High

1151780

RHOH
Rho-related GTP-binding protein RhoH

1

4

High-throughput

0.437

High

1270902

RHOU
Rho-related GTP-binding protein RhoU

1

5

High-throughput

0.437

High

1294209

GOLI
E3 ubiquitin-protein ligase RNF130

1

2

High-throughput

0.437

High

1333703

RHOJ
Rho-related GTP-binding protein RhoJ

1

4

High-throughput

0.437

High

1333720

S12A6
Solute carrier family 12 member 6

1

1

Small-scale

0.437

High

858987

RL27A
Large ribosomal subunit protein uL15

1

0

High-throughput

0.426

High

1333670

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.426

High

1333724

S27A5
Long-chain fatty acid transport protein 5

1

0

High-throughput

0.426

High

539724

ACHB
Acetylcholine receptor subunit beta

1

2

High-throughput

0.407

High

1068879

NIPA4
Magnesium transporter NIPA4

1

1

High-throughput

0.407

High

1131572

MFS10
Major facilitator superfamily domain-containing protein 10

1

2

High-throughput

0.407

High

1194524

SL9C1
Solute carrier family 9 member C1

1

2

High-throughput

0.407

High

1199082

CTL4
Choline transporter-like protein 4

1

3

High-throughput

0.407

High

1215252

SL9C2
Sodium/hydrogen exchanger 11

1

2

High-throughput

0.407

High

1224946

S22AA
Solute carrier family 22 member 10

1

3

High-throughput

0.407

High

1273773

NIPA1
Magnesium transporter NIPA1

1

1

High-throughput

0.407

High

1309755

CTL2
Choline transporter-like protein 2

1

3

High-throughput

0.407

High

1326589

CTL3
Choline transporter-like protein 3

1

3

High-throughput

0.407

High

1326965

SVOP
Synaptic vesicle 2-related protein

1

2

High-throughput

0.407

High

1333671

CTL5
Choline transporter-like protein 5

1

3

High-throughput

0.407

High

1333692

SL9A7
Sodium/hydrogen exchanger 7

1

2

High-throughput

0.407

High

1333699

S12A9
Solute carrier family 12 member 9

1

1

High-throughput

0.407

High

1333718

NPCL1
NPC1-like intracellular cholesterol transporter 1

1

1

High-throughput

0.407

High

142142

NPT3
Sodium-dependent phosphate transport protein 3

2

0

High-throughput

0.328

High

839593

HUTH
Histidine ammonia-lyase

2

0

High-throughput

0.318

High

1213779

KPRP
Keratinocyte proline-rich protein

2

0

High-throughput

0.318

High

1333680

UFD1
Ubiquitin recognition factor in ER-associated degradation protein 1

2

0

High-throughput

0.318

High

1333719

PCYOX
Prenylcysteine oxidase 1

2

0

High-throughput

0.318

High

1333721

CBPA4
Carboxypeptidase A4

2

0

High-throughput

0.318

High

49802

CLRN2
Clarin-2

1

0

High-throughput

0.279

Low

161489

KMT2D
Histone-lysine N-methyltransferase 2D

1

0

High-throughput

0.279

Low

163386

GBRD
Gamma-aminobutyric acid receptor subunit delta

1

0

High-throughput

0.279

Low

320475

TM63A
Mechanosensitive cation channel TMEM63A

1

0

High-throughput

0.279

Low

325335

OR2A4
Olfactory receptor 2A4

1

0

High-throughput

0.279

Low

347815

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.279

Low

354139

CLPT1
Putative lipid scramblase CLPTM1

1

0

High-throughput

0.279

Low

470320

NEP
Neprilysin

1

0

Small-scale

0.279

Low

820568

GPV
Platelet glycoprotein V

1

0

High-throughput

0.279

Low

828408

PEX19
Peroxisomal biogenesis factor 19

1

0

High-throughput

0.279

Low

874824

SPB4
Serpin B4

1

0

High-throughput

0.279

Low

901395

RAB7A
Ras-related protein Rab-7a

1

0

High-throughput

0.279

Low

910588

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

0

High-throughput

0.279

Low

996499

ACTS
Actin, alpha skeletal muscle

1

0

High-throughput

0.279

Low

1008244

PRKDC
DNA-dependent protein kinase catalytic subunit

1

0

High-throughput

0.279

Low

1145016

RAB35
Ras-related protein Rab-35

1

0

High-throughput

0.279

Low

1204515

XKR6
XK-related protein 6

1

0

High-throughput

0.279

Low

1207723

TMM31
Transmembrane protein 31

1

0

High-throughput

0.279

Low

1209969

TM201
Transmembrane protein 201

1

0

High-throughput

0.279

Low

1242866

S39A4
Zinc transporter ZIP4

1

0

High-throughput

0.279

Low

1287177

T150A
Transmembrane protein 150A

1

0

High-throughput

0.279

Low

1308501

CNGA4
Cyclic nucleotide-gated channel alpha-4

1

0

High-throughput

0.279

Low

1310235

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.279

Low

1326654

IT70B
Intraflagellar transport protein 70B

1

0

High-throughput

0.279

Low

1333570

SIDT2
SID1 transmembrane family member 2

1

0

High-throughput

0.279

Low

1333696

ABHEA
Protein ABHD14A

1

0

High-throughput

0.279

Low

1333712

GDE1
Glycerophosphodiester phosphodiesterase 1

1

0

High-throughput

0.279

Low

1333713

CALL5
Calmodulin-like protein 5

1

0

High-throughput

0.279

Low

1333723

CLC11
C-type lectin domain family 11 member A

1

0

High-throughput

0.279

Low

1333725

SC6A5
Sodium- and chloride-dependent glycine transporter 2

1

0

High-throughput

0.279

Low

155122

SOCS2
Suppressor of cytokine signaling 2

1

0

High-throughput

0.269

Low

246055

KIF1B
Kinesin-like protein KIF1B

1

0

High-throughput

0.268

Low

415734

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.268

Low

1123720

DCTN1
Dynactin subunit 1

1

0

High-throughput

0.268

Low

1050479

UBE3A
Ubiquitin-protein ligase E3A

1

0

High-throughput

0.257

Low

48029

RBM47
RNA-binding protein 47

1

0

High-throughput

0.249

Low

61557

VWA8
von Willebrand factor A domain-containing protein 8

1

0

High-throughput

0.249

Low

218475

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

294031

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

471138

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.249

Low

560020

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

0

High-throughput

0.249

Low

567448

TCTP
Translationally-controlled tumor protein

1

0

High-throughput

0.249

Low

582592

PPAP
Prostatic acid phosphatase

1

0

High-throughput

0.249

Low

589179

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

695959

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

766698

PHB1
Prohibitin 1

1

0

High-throughput

0.249

Low

831076

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

851956

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.249

Low

927064

ATX3
Ataxin-3

1

0

Small-scale

0.249

Low

975130

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.249

Low

1004836

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1178257

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

1241695

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.249

Low

1254672

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1272940

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

0

High-throughput

0.249

Low

1276490

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1289815

PAQR2
Adiponectin receptor protein 2

1

0

Small-scale

0.249

Low

1333682

S2546
Mitochondrial outer membrane protein SLC25A46

1

0

High-throughput

0.249

Low

1333688

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.249

Low

1333694

DUS9
Dual specificity protein phosphatase 9

1

0

High-throughput

0.249

Low

1333700

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.249

Low

1333702

S2551
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51

1

0

High-throughput

0.249

Low

1333704

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1333706

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.249

Low

1333709

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.249

Low

1333710

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

0

High-throughput

0.249

Low

1333716

ZMYM2
Zinc finger MYM-type protein 2

1

0

High-throughput

0.249

Low

1272399

GET4
Golgi to ER traffic protein 4 homolog

1

0

High-throughput

0.238

Low

1333677

LMO7
LIM domain only protein 7

1

0

High-throughput

0.238

Low

4744

A0A183YE00
Tubulin beta chain

1

0

High-throughput

0.232

Low

220610

AKA10
A-kinase anchor protein 10, mitochondrial

1

0

High-throughput

0.232

Low

510098

S35E2
Solute carrier family 35 member E2A

1

0

High-throughput

0.232

Low

613398

VINC
Vinculin

1

0

High-throughput

0.232

Low

972909

RS18
Small ribosomal subunit protein uS13

1

0

High-throughput

0.232

Low

1202037

H90B2
Putative heat shock protein HSP 90-beta 2

1

0

High-throughput

0.232

Low

1308773

S41A1
Solute carrier family 41 member 1

1

0

High-throughput

0.232

Low

1316654

S38A6
Solute carrier family 38 member 6

1

0

High-throughput

0.232

Low

1333672

TM104
Transmembrane protein 104

1

0

High-throughput

0.232

Low

1333678

S13A3
Na(+)/dicarboxylate cotransporter 3

1

0

High-throughput

0.232

Low

1333690

S26A8
Testis anion transporter 1

1

0

High-throughput

0.232

Low

1333705

VIAAT
Vesicular inhibitory amino acid transporter

1

0

High-throughput

0.232

Low

1333707

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025