Interactor 1: IL1R1 (P14778)
Interleukin-1 receptor type 1 (IL-1R-1) (IL-1RT-1) (IL-1RT1) (EC 3.2.2.6) (CD121 antigen-like family member A) (Interleukin-1 receptor alpha) (IL-1R-alpha) (Interleukin-1 receptor type I) (p80) (CD antigen CD121a) [Cleaved into: Interleukin-1 receptor type 1, membrane form (mIL-1R1) (mIL-1RI); Interleukin-1 receptor type 1, soluble form (sIL-1R1) (sIL-1RI)]
Gene: IL1R1

Interactor 2: TOLIP (Q9H0E2)
Toll-interacting protein
Gene: TOLLIP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 17113392, 10854325
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005576 - extracellular region
GO:0006954 - inflammatory response
GO:0070498 - interleukin-1-mediated signaling pathway
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 569
Hs

1 274
+ Mm
+ Rn
+ Hs
+ Hs
+ Mm
+ Rn
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024