Interactor 1: MMP9 (P14780)
Matrix metalloproteinase-9 (MMP-9) (EC 3.4.24.35) (92 kDa gelatinase) (92 kDa type IV collagenase) (Gelatinase B) (GELB) [Cleaved into: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9]
Gene: MMP9

Interactor 2: MMP9 (P14780)
Matrix metalloproteinase-9 (MMP-9) (EC 3.4.24.35) (92 kDa gelatinase) (92 kDa type IV collagenase) (Gelatinase B) (GELB) [Cleaved into: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9]
Gene: MMP9

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.853

The method score is based on:

Property Details
Experiments 17937912, 18077379, 23601700
Identification Methods molecular sieving, comigration in non denaturing gel electrophoresis, comigration in gel electrophoresis, zymography
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains fn2~fn2, Hemopexin~Hemopexin, Hemopexin~Peptidase_M10, Peptidase_M10~Peptidase_M10
Common GO terms GO:0001501 - skeletal system development
GO:0001934 - positive regulation of protein phosphorylation
GO:0004175 - endopeptidase activity
GO:0004222 - metalloendopeptidase activity
GO:0004252 - serine-type endopeptidase activity
and 38 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 707
Hs

1 707
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024