HitPredict

Interactor 1: MMP9 (P14780)
Matrix metalloproteinase-9 (MMP-9) (EC 3.4.24.35) (92 kDa gelatinase) (92 kDa type IV collagenase) (Gelatinase B) (GELB) [Cleaved into: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9]
Gene: MMP9

Interactor 2: ELN (P15502)
Elastin (Tropoelastin)
Gene: ELN

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	20345904
Identification Methods	protease assay
Interaction Type	cleavage reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0062023 - collagen-containing extracellular matrix
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 707 Hs			1 786
+	Hs
		358595 MMP9_HUMAN (1-707): 0: 862: 100.00		CO2A1_HUMAN (315-786): 1.66e-28: 125: 18.29
+	Hs
		358650 MMP9_HUMAN (1-707): 0: 862: 100.00		CO4A1_HUMAN (300-785): 1.09e-21: 103: 16.97
+	Hs
		441053 MMP9_HUMAN (1-707): 0: 862: 100.00		CO4A2_HUMAN (393-783): 3.33e-20: 98.7: 14.26
+	Hs
		436005 MMP9_HUMAN (1-707): 0: 862: 100.00		CO1A2_HUMAN (531-785): 2.01e-13: 76.3: 18.39
+	Hs
		540415 MMP9_HUMAN (1-707): 0: 862: 100.00		CO5A1_HUMAN (381-786): 5.16e-12: 72.1: 15.53
+	Hs
		517985 MMP9_HUMAN (1-707): 0: 862: 100.00		CO6A2_HUMAN (460-678): 2.48e-09: 63.1: 20.33
+	Hs
		548783 MMP12_HUMAN (7-274): 1.14e-87: 284: 31.47		ELN_HUMAN (1-786): 3.24e-43: 170: 100.00
+	Hs
		436002 MMP3_HUMAN (8-272): 4.38e-93: 299: 37.46		CO1A2_HUMAN (531-785): 2.01e-13: 76.3: 18.39
+	Hs
		372723 MMP1_HUMAN (31-238): 9.64e-87: 282: 42.67		CO1A2_HUMAN (531-785): 2.01e-13: 76.3: 18.39
+	Hs
		436012 MMP8_HUMAN (35-295): 3.17e-81: 267: 32.01		CO1A2_HUMAN (531-785): 2.01e-13: 76.3: 18.39
+	Hs
		436025 MMP16_HUMAN (45-280): 2.33e-72: 248: 32.35		CO1A2_HUMAN (531-785): 2.01e-13: 76.3: 18.39
+	Hs
		436022 MMP14_HUMAN (33-254): 2.47e-70: 241: 32.43		CO1A2_HUMAN (531-785): 2.01e-13: 76.3: 18.39
+	Hs
		436024 MMP15_HUMAN (45-279): 2.87e-67: 235: 31.02		CO1A2_HUMAN (531-785): 2.01e-13: 76.3: 18.39
+	Hs
		448874 MMP7_HUMAN (348-449): 6.94e-37: 141: 34.62		ELN_HUMAN (1-786): 3.24e-43: 170: 100.00
+	Hs
		358587 MMP2_HUMAN (576-707): 2.91e-20: 97.5: 15.71		CO2A1_HUMAN (315-786): 1.66e-28: 125: 18.29
+	Hs
		358647 MMP2_HUMAN (576-707): 2.91e-20: 97.5: 15.71		CO4A1_HUMAN (300-785): 1.09e-21: 103: 16.97
+	Hs
		358454 MMP2_HUMAN (576-707): 2.91e-20: 97.5: 15.71		CO1A1_HUMAN (1-458): 2.46e-20: 99.1: 17.73
+	Hs
		439220 MMP2_HUMAN (576-707): 2.91e-20: 97.5: 15.71		CO4A2_HUMAN (393-783): 3.33e-20: 98.7: 14.26
+	Hs
		436001 MMP2_HUMAN (576-707): 2.91e-20: 97.5: 15.71		CO1A2_HUMAN (531-785): 2.01e-13: 76.3: 18.39
+	Hs
		439222 MMP2_HUMAN (576-707): 2.91e-20: 97.5: 15.71		CO6A2_HUMAN (460-678): 2.48e-09: 63.1: 20.33