HitPredict

Interactor 1: MMP9 (P14780)
Matrix metalloproteinase-9 (MMP-9) (EC 3.4.24.35) (92 kDa gelatinase) (92 kDa type IV collagenase) (Gelatinase B) (GELB) [Cleaved into: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9]
Gene: MMP9

Interactor 2: COL12 (Q5KU26)
Collectin-12 (Collectin placenta protein 1) (CL-P1) (hCL-P1) (Nurse cell scavenger receptor 2) (Scavenger receptor class A member 4) (Scavenger receptor with C-type lectin)
Gene: COLEC12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Lectin_C~fn2
Common GO terms	GO:0005615 - extracellular space GO:0062023 - collagen-containing extracellular matrix
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 707 Hs			1 742
+	Hs
		540416 MMP9_HUMAN (1-707): 0: 862: 100.00		SFTPD_HUMAN (400-732): 3.96e-63: 217: 26.52
+	Hs
		530364 MMP9_HUMAN (1-707): 0: 862: 100.00		CSPG2_HUMAN (559-742): 1.91e-45: 178: 25.79
+	Hs
		540433 MMP9_HUMAN (1-707): 0: 862: 100.00		SCAR3_HUMAN (2-555): 1.35e-43: 168: 31.99
+	Hs
		517985 MMP9_HUMAN (1-707): 0: 862: 100.00		CO6A2_HUMAN (299-630): 8.24e-35: 144: 17.78
+	Hs
		441053 MMP9_HUMAN (1-707): 0: 862: 100.00		CO4A2_HUMAN (419-634): 6.73e-18: 91.1: 19.44
+	Hs
		517917 MMP9_HUMAN (1-707): 0: 862: 100.00		CO6A1_HUMAN (496-588): 5.95e-12: 71.2: 42.42
+	Hs
		358595 MMP9_HUMAN (1-707): 0: 862: 100.00		CO2A1_HUMAN (446-584): 7.01e-11: 68.2: 37.69
+	Hs
		436005 MMP9_HUMAN (1-707): 0: 862: 100.00		CO1A2_HUMAN (394-477): 1.31e-09: 64.1: 25.00
+	Hs
		358650 MMP9_HUMAN (1-707): 0: 862: 100.00		CO4A1_HUMAN (451-641): 3.9e-09: 62.6: 28.63
+	Hs
		799575 MMP13_HUMAN (1-277): 5.97e-98: 311: 35.15		PGCB_HUMAN (436-742): 1.73e-50: 192: 21.22
+	Hs
		439274 MMP3_HUMAN (8-272): 4.38e-93: 299: 37.46		PGCB_HUMAN (436-742): 1.73e-50: 192: 21.22
+	Hs
		448913 MMP10_HUMAN (6-235): 1.56e-89: 290: 40.41		PGCB_HUMAN (436-742): 1.73e-50: 192: 21.22
+	Hs
		439264 MMP3_HUMAN (8-272): 4.38e-93: 299: 37.46		PGCA_HUMAN (573-742): 5.99e-46: 180: 26.74
+	Hs
		372741 MMP1_HUMAN (31-238): 9.64e-87: 282: 42.67		PGCB_HUMAN (436-742): 1.73e-50: 192: 21.22
+	Hs
		612141 MMP8_HUMAN (35-295): 3.17e-81: 267: 32.01		PGCB_HUMAN (436-742): 1.73e-50: 192: 21.22
+	Hs
		436002 MMP3_HUMAN (8-272): 4.38e-93: 299: 37.46		CO1A2_HUMAN (394-477): 1.31e-09: 64.1: 25.00
+	Hs
		372723 MMP1_HUMAN (31-238): 9.64e-87: 282: 42.67		CO1A2_HUMAN (394-477): 1.31e-09: 64.1: 25.00
+	Hs
		436012 MMP8_HUMAN (35-295): 3.17e-81: 267: 32.01		CO1A2_HUMAN (394-477): 1.31e-09: 64.1: 25.00
+	Hs
		436025 MMP16_HUMAN (45-280): 2.33e-72: 248: 32.35		CO1A2_HUMAN (394-477): 1.31e-09: 64.1: 25.00
+	Hs
		436022 MMP14_HUMAN (33-254): 2.47e-70: 241: 32.43		CO1A2_HUMAN (394-477): 1.31e-09: 64.1: 25.00