Protein: STX16
Syntaxin-16 (Syn16)

Gene: STX16
Organism: Homo sapiens
Interactions: 80
UniProt ID: O14662

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0000149 - SNARE binding
GO:0005484 - SNAP receptor activity
GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

160920

VPS45
Vacuolar protein sorting-associated protein 45

6

20

High-throughput

0.948

High

160855

VAMP5
Vesicle-associated membrane protein 5

5

20

High-throughput

0.936

High

160854

VAMP4
Vesicle-associated membrane protein 4

4

20

Small-scale

0.894

High

160887

STX4
Syntaxin-4

3

16

High-throughput

0.871

High

160914

SNAB
Beta-soluble NSF attachment protein

3

20

High-throughput

0.871

High

160876

SNAA
Alpha-soluble NSF attachment protein

3

20

High-throughput

0.871

High

160910

VTI1A
Vesicle transport through interaction with t-SNAREs homolog 1A

2

20

High-throughput

0.789

High

160870

STX2
Syntaxin-2

2

16

High-throughput

0.783

High

160893

STX1A
Syntaxin-1A

2

17

High-throughput

0.783

High

160847

STX16
Syntaxin-16

1

16

High-throughput

0.691

High

160849

STX7
Syntaxin-7

1

16

High-throughput

0.691

High

160852

STX6
Syntaxin-6

1

20

High-throughput

0.691

High

160853

STX10
Syntaxin-10

1

20

High-throughput

0.691

High

160907

SCFD1
Sec1 family domain-containing protein 1

1

20

High-throughput

0.691

High

160913

SNAG
Gamma-soluble NSF attachment protein

1

20

High-throughput

0.691

High

160857

SNP29
Synaptosomal-associated protein 29

3

20

High-throughput

0.665

High

160892

VAMP3
Vesicle-associated membrane protein 3

1

20

Small-scale

0.618

High

160906

GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5

2

5

High-throughput

0.601

High

160903

ZDH17
Palmitoyltransferase ZDHHC17

1

8

High-throughput

0.582

High

160902

STX12
Syntaxin-12

1

16

High-throughput

0.575

High

160874

MEOX2
Homeobox protein MOX-2

1

2

High-throughput

0.573

High

160860

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

160911

SAAL1
Protein SAAL1

2

1

High-throughput

0.549

High

160850

ZW10
Centromere/kinetochore protein zw10 homolog

1

2

High-throughput

0.536

High

160867

CRCM
Colorectal mutant cancer protein

1

2

High-throughput

0.536

High

160873

NSF
Vesicle-fusing ATPase

1

15

High-throughput

0.536

High

160889

SEC20
Vesicle transport protein SEC20

1

7

High-throughput

0.536

High

160921

STX18
Syntaxin-18

1

7

High-throughput

0.536

High

160859

TFR1
Transferrin receptor protein 1

1

3

High-throughput

0.515

High

160861

A4
Amyloid-beta precursor protein

1

6

High-throughput

0.515

High

160872

HD
Huntingtin

1

7

High-throughput

0.515

High

160905

MCLN2
Mucolipin-2

1

0

High-throughput

0.513

High

160915

G3ST2
Galactose-3-O-sulfotransferase 2

1

0

High-throughput

0.513

High

160886

PTN12
Tyrosine-protein phosphatase non-receptor type 12

1

7

High-throughput

0.508

High

160899

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.501

High

160912

VPS50
Syndetin

1

3

Small-scale

0.500

High

160877

H2BFS
Histone H2B type F-S

1

0

High-throughput

0.493

High

160897

S39A4
Zinc transporter ZIP4

1

10

High-throughput

0.489

High

126361

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

160848

BET1
BET1 homolog

1

20

High-throughput

0.479

High

160851

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.479

High

160862

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.479

High

160864

LAMP1
Lysosome-associated membrane glycoprotein 1

1

6

High-throughput

0.479

High

160865

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

160869

EPHA2
Ephrin type-A receptor 2

1

4

High-throughput

0.479

High

160875

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.479

High

160878

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

160879

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

160880

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

160881

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

160882

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

160883

RNF4
E3 ubiquitin-protein ligase RNF4

1

6

High-throughput

0.479

High

160884

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

160888

TP4A2
Protein tyrosine phosphatase type IVA 2

1

5

Small-scale

0.479

High

160890

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

High-throughput

0.479

High

160891

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.479

High

160898

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.479

High

160900

ATG9A
Autophagy-related protein 9A

1

2

High-throughput

0.479

High

160909

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

160917

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

160923

WNK2
Serine/threonine-protein kinase WNK2

1

3

High-throughput

0.479

High

133704

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

0

High-throughput

0.458

High

160895

KAD9
Adenylate kinase 9

1

0

High-throughput

0.458

High

160916

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

160919

DUS22
Dual specificity protein phosphatase 22

1

0

High-throughput

0.458

High

160922

PPM1H
Protein phosphatase 1H

1

0

High-throughput

0.458

High

160863

TAU
Microtubule-associated protein tau

1

5

High-throughput

0.445

High

160885

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

2

High-throughput

0.445

High

160896

NPAL3
NIPA-like protein 3

1

4

High-throughput

0.445

High

160918

ANKH
Mineralization regulator ANKH

1

1

High-throughput

0.445

High

160866

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

160868

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.437

High

160871

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

160901

TMM17
Transmembrane protein 17

1

2

High-throughput

0.437

High

160904

SL9A9
Sodium/hydrogen exchanger 9

1

3

High-throughput

0.407

High

160908

CTR3
Cationic amino acid transporter 3

1

10

High-throughput

0.407

High

160856

SPDEF
SAM pointed domain-containing Ets transcription factor

1

0

High-throughput

0.269

Low

160858

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

160894

COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025