Protein: MERTK
Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase MerTK)

Gene: MERTK
Organism: Homo sapiens
Interactions: 117
UniProt ID: Q12866

Gene Ontology (top 5):
GO:0001750 - photoreceptor outer segment
GO:0001779 - natural killer cell differentiation
GO:0001818 - negative regulation of cytokine production
GO:0004714 - transmembrane receptor protein tyrosine kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1018322

MERTK
Tyrosine-protein kinase Mer

2

19

Small-scale

0.812

High

1018324

GAS6
Growth arrest-specific protein 6

2

20

Small-scale

0.768

High

674409

UFO
Tyrosine-protein kinase receptor UFO

2

19

Small-scale

0.767

High

383769

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

Small-scale

0.713

High

234508

DSCAM
Cell adhesion molecule DSCAM

1

12

High-throughput

0.698

High

548695

VAV
Proto-oncogene vav

1

20

Small-scale

0.653

High

396726

S10A8
Protein S100-A8

1

5

High-throughput

0.646

High

646846

1433T
14-3-3 protein theta

1

20

High-throughput

0.618

High

683304

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.618

High

909494

1433E
14-3-3 protein epsilon

1

5

High-throughput

0.618

High

992569

ACK1
Activated CDC42 kinase 1

1

19

Small-scale

0.618

High

1018341

ARHG2
Rho guanine nucleotide exchange factor 2

1

20

High-throughput

0.618

High

1018361

RASF1
Ras association domain-containing protein 1

1

13

High-throughput

0.618

High

1018375

FBW1A
F-box/WD repeat-containing protein 1A

1

3

High-throughput

0.618

High

924527

GRB2
Growth factor receptor-bound protein 2

1

20

Small-scale

0.590

High

1018382

NEMO
NF-kappa-B essential modulator

1

14

High-throughput

0.561

High

902553

SUMO2
Small ubiquitin-related modifier 2

1

1

High-throughput

0.553

High

1018350

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

6

High-throughput

0.553

High

1018370

FBW1B
F-box/WD repeat-containing protein 11

1

3

High-throughput

0.553

High

363778

ALBU
Albumin

1

2

High-throughput

0.536

High

449247

LEG1
Galectin-1

1

5

High-throughput

0.536

High

653574

CALR
Calreticulin

1

20

High-throughput

0.536

High

671648

PEBP1
Phosphatidylethanolamine-binding protein 1

1

5

High-throughput

0.536

High

1018328

CDC37
Hsp90 co-chaperone Cdc37

1

20

High-throughput

0.536

High

1018369

FBX2
F-box only protein 2

1

13

High-throughput

0.536

High

1018381

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

3

High-throughput

0.536

High

1018346

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

18

High-throughput

0.501

High

215132

LANC1
Glutathione S-transferase LANCL1

1

3

High-throughput

0.500

High

268456

BAF
Barrier-to-autointegration factor

1

9

High-throughput

0.500

High

936034

HBA
Hemoglobin subunit alpha

1

5

High-throughput

0.500

High

1018333

YTHD3
YTH domain-containing family protein 3

1

13

High-throughput

0.500

High

1018353

YTHD1
YTH domain-containing family protein 1

1

9

High-throughput

0.500

High

1018378

YTHD2
YTH domain-containing family protein 2

1

14

High-throughput

0.500

High

417714

G6PI
Glucose-6-phosphate isomerase

1

3

High-throughput

0.489

High

852031

ROA3
Heterogeneous nuclear ribonucleoprotein A3

1

5

High-throughput

0.489

High

996635

SSRP1
FACT complex subunit SSRP1

1

5

High-throughput

0.489

High

1018379

SP16H
FACT complex subunit SPT16

1

1

High-throughput

0.489

High

208571

TIM44
Mitochondrial import inner membrane translocase subunit TIM44

1

5

High-throughput

0.479

High

316634

ACSL3
Fatty acid CoA ligase Acsl3

1

6

High-throughput

0.479

High

431788

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.479

High

438114

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.479

High

456558

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

6

High-throughput

0.479

High

531813

PDIA4
Protein disulfide-isomerase A4

1

20

High-throughput

0.479

High

780689

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

2

High-throughput

0.479

High

796841

NAMPT
Nicotinamide phosphoribosyltransferase

1

3

High-throughput

0.479

High

838630

GDIB
Rab GDP dissociation inhibitor beta

1

1

High-throughput

0.479

High

838799

EMD
Emerin

1

13

High-throughput

0.479

High

839579

SERPH
Serpin H1

1

8

High-throughput

0.479

High

885238

EPIPL
Epiplakin

1

12

High-throughput

0.479

High

896423

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

7

High-throughput

0.479

High

914742

CNBP
CCHC-type zinc finger nucleic acid binding protein

1

5

High-throughput

0.479

High

944208

PRKDC
DNA-dependent protein kinase catalytic subunit

1

18

High-throughput

0.479

High

981073

LGUL
Lactoylglutathione lyase

1

1

High-throughput

0.479

High

997549

NSUN2
RNA cytosine C(5)-methyltransferase NSUN2

1

10

High-throughput

0.479

High

1018325

SYK
Lysine--tRNA ligase

1

7

High-throughput

0.479

High

1018334

RASF3
Ras association domain-containing protein 3

1

4

High-throughput

0.479

High

1018338

IPO4
Importin-4

1

8

High-throughput

0.479

High

1018339

DNJC9
DnaJ homolog subfamily C member 9

1

20

High-throughput

0.479

High

1018342

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

7

High-throughput

0.479

High

1018343

DDX27
Probable ATP-dependent RNA helicase DDX27

1

14

High-throughput

0.479

High

1018345

RBM14
RNA-binding protein 14

1

11

High-throughput

0.479

High

1018349

PARK7
Parkinson disease protein 7

1

2

High-throughput

0.479

High

1018351

NTPCR
Cancer-related nucleoside-triphosphatase

1

11

High-throughput

0.479

High

1018352

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

7

High-throughput

0.479

High

1018354

NAT10
RNA cytidine acetyltransferase

1

2

High-throughput

0.479

High

1018355

SAV1
Protein salvador homolog 1

1

18

High-throughput

0.479

High

1018363

MDN1
Midasin

1

19

High-throughput

0.479

High

1018364

DD19A
ATP-dependent RNA helicase DDX19A

1

5

High-throughput

0.479

High

1018367

BAZ1B
Tyrosine-protein kinase BAZ1B

1

10

High-throughput

0.479

High

1018368

STML2
Stomatin-like protein 2, mitochondrial

1

7

High-throughput

0.479

High

1018371

MRT4
mRNA turnover protein 4 homolog

1

7

High-throughput

0.479

High

1018374

SMC3
Structural maintenance of chromosomes protein 3

1

14

High-throughput

0.479

High

1018377

HYOU1
Hypoxia up-regulated protein 1

1

20

High-throughput

0.479

High

1018380

SRPRB
Signal recognition particle receptor subunit beta

1

20

High-throughput

0.479

High

430461

APT
Adenine phosphoribosyltransferase

1

0

High-throughput

0.458

High

508969

TOP2A
DNA topoisomerase 2-alpha

1

0

High-throughput

0.458

High

521261

SKI
Ski oncogene

1

0

Small-scale

0.458

High

782895

GARS
Glycine--tRNA ligase

1

0

High-throughput

0.458

High

355146

HBD
Hemoglobin subunit delta

1

5

High-throughput

0.457

High

1018323

TRA2A
Transformer-2 protein homolog alpha

1

6

High-throughput

0.457

High

1018327

SAFB1
Scaffold attachment factor B1

1

14

High-throughput

0.457

High

130493

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

8

High-throughput

0.437

High

240568

DPM1
Dolichol-phosphate mannosyltransferase subunit 1

1

5

High-throughput

0.437

High

260861

H2AY
Core histone macro-H2A.1

1

7

High-throughput

0.437

High

273780

NU155
Nuclear pore complex protein Nup155

1

6

High-throughput

0.437

High

314312

AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1

1

2

High-throughput

0.437

High

398696

IF2A
Eukaryotic translation initiation factor 2 subunit 1

1

7

High-throughput

0.437

High

438753

SRPRA
Signal recognition particle receptor subunit alpha

1

9

High-throughput

0.437

High

455373

PARP1
Poly [ADP-ribose] polymerase 1

1

11

High-throughput

0.437

High

577628

SON
Protein SON

1

12

High-throughput

0.437

High

800359

CBX5
Chromobox protein homolog 5

1

2

High-throughput

0.437

High

849094

DHB4
Peroxisomal multifunctional enzyme type 2

1

3

High-throughput

0.437

High

946861

RT22
Small ribosomal subunit protein mS22

1

2

High-throughput

0.437

High

1018326

RRS1
Ribosome biogenesis regulatory protein homolog

1

2

High-throughput

0.437

High

1018329

MIC60
MICOS complex subunit MIC60

1

1

High-throughput

0.437

High

1018330

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

9

High-throughput

0.437

High

1018331

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

7

High-throughput

0.437

High

1018332

ZN326
DBIRD complex subunit ZNF326

1

5

High-throughput

0.437

High

1018335

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

16

High-throughput

0.437

High

1018336

NUP93
Nuclear pore complex protein Nup93

1

5

High-throughput

0.437

High

1018337

KRI1
Protein KRI1 homolog

1

12

High-throughput

0.437

High

1018340

NU205
Nuclear pore complex protein Nup205

1

7

High-throughput

0.437

High

1018347

RBM15
RNA-binding protein 15

1

9

High-throughput

0.437

High

1018348

UHRF1
E3 ubiquitin-protein ligase UHRF1

1

6

High-throughput

0.437

High

1018356

CCD86
Coiled-coil domain-containing protein 86

1

2

High-throughput

0.437

High

1018357

RPF2
Ribosome production factor 2 homolog

1

1

High-throughput

0.437

High

1018358

SFXN1
Sideroflexin-1

1

1

High-throughput

0.437

High

1018359

ZFP14
Zinc finger protein 14 homolog

1

4

High-throughput

0.437

High

1018360

SSF1
Suppressor of SWI4 1 homolog

1

1

High-throughput

0.437

High

1018365

RBM28
RNA-binding protein 28

1

9

High-throughput

0.437

High

1018366

H2AW
Core histone macro-H2A.2

1

6

High-throughput

0.437

High

1018372

RALY
RNA-binding protein Raly

1

2

High-throughput

0.437

High

1018373

RL26L
Ribosomal protein uL24-like

1

2

High-throughput

0.437

High

1018376

CHTOP
Chromatin target of PRMT1 protein

1

5

High-throughput

0.437

High

1018344

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.282

High

1018362

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024