Interactor 1: IL2RB (P14784)
Interleukin-2 receptor subunit beta (IL-2 receptor subunit beta) (IL-2R subunit beta) (IL-2RB) (High affinity IL-2 receptor subunit beta) (Interleukin-15 receptor subunit beta) (p70-75) (p75) (CD antigen CD122)
Gene: IL2RB
Interactor 2: IL15 (P40933)
Interleukin-15 (IL-15)
Gene: IL15
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.84 | 1.00 | 0.920 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10903799, 8178155, 8026467, 25416956, 23104097 |
| Identification Methods | coimmunoprecipitation, cross-linking study, biochemical, protein cross-linking with a bifunctional reagent, mammalian protein protein interaction trap, surface plasmon resonance |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | IL15~IL2RB_N1 |
| Common GO terms | GO:0005768 - endosome GO:0005829 - cytosol GO:0007165 - signal transduction GO:0035723 - interleukin-15-mediated signaling pathway GO:0050766 - positive regulation of phagocytosis |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
