Protein: EFR3A
Protein EFR3 homolog A (Protein EFR3-like)

Gene: EFR3A
Organism: Homo sapiens
Interactions: 114
UniProt ID: Q14156

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0016082 - synaptic vesicle priming
GO:0046854 - phosphatidylinositol phosphate biosynthetic process
GO:0072659 - protein localization to plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

478683

HXB5
Homeobox protein Hox-B5

3

1

High-throughput

0.667

High

375512

RASK
GTPase KRas

3

10

High-throughput

0.640

High

1122017

A16L1
Autophagy-related protein 16-1

3

1

High-throughput

0.633

High

1122040

LPAR4
Lysophosphatidic acid receptor 4

2

1

High-throughput

0.628

High

616752

SDC1
Syndecan-1

2

0

High-throughput

0.602

High

978002

RHOB
Rho-related GTP-binding protein RhoB

2

16

High-throughput

0.584

High

1122013

TIGD5
Tigger transposable element-derived protein 5

2

1

High-throughput

0.574

High

1122019

CXB7
Gap junction beta-7 protein

2

5

High-throughput

0.574

High

396092

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

1122032

ARHG2
Rho guanine nucleotide exchange factor 2

2

0

High-throughput

0.559

High

1122025

T185A
Transmembrane protein 185A

2

1

High-throughput

0.558

High

1122010

NTRK3
NT-3 growth factor receptor

1

3

High-throughput

0.536

High

1122026

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

1

1

High-throughput

0.536

High

1122042

S22A4
Solute carrier family 22 member 4

1

1

High-throughput

0.536

High

1122054

GPR45
Probable G-protein coupled receptor 45

1

3

High-throughput

0.536

High

276906

VPS4B
Vacuolar protein sorting-associated protein 4B

1

0

High-throughput

0.513

High

466894

ACM4
Muscarinic acetylcholine receptor M4

1

0

High-throughput

0.513

High

638415

FPR1
fMet-Leu-Phe receptor

1

0

High-throughput

0.513

High

702775

5HT2C
5-hydroxytryptamine receptor 2C

1

0

High-throughput

0.513

High

880140

PTH2R
Parathyroid hormone 2 receptor

1

0

High-throughput

0.513

High

1092755

MALL
MAL-like protein

1

0

High-throughput

0.513

High

1122016

FBX31
F-box only protein 31

1

0

High-throughput

0.513

High

1122028

AQP3
Aquaporin-3

1

0

High-throughput

0.513

High

1122031

KIFA3
Kinesin-associated protein 3

1

0

High-throughput

0.513

High

1122036

OPALI
Opalin

1

0

High-throughput

0.513

High

1122049

ATG3
Ubiquitin-like-conjugating enzyme ATG3

1

0

High-throughput

0.513

High

1122055

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

0

High-throughput

0.513

High

137329

ELL2
RNA polymerase II elongation factor ELL2

1

2

High-throughput

0.489

High

706124

S10A2
Protein S100-A2

1

2

High-throughput

0.489

High

1122009

UB2V2
Ubiquitin-conjugating enzyme E2 variant 2

1

2

High-throughput

0.489

High

1122014

PEAR1
Platelet endothelial aggregation receptor 1

1

1

High-throughput

0.489

High

126591

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

299189

FLOT1
Flotillin-1

1

1

High-throughput

0.479

High

303131

RGS20
Regulator of G-protein signaling 20

1

3

High-throughput

0.479

High

341052

DIRA3
GTP-binding protein Di-Ras3

1

3

High-throughput

0.479

High

373927

RASN
GTPase NRas

1

10

High-throughput

0.479

High

374597

RASH
GTPase HRas

1

6

High-throughput

0.479

High

440071

LCK
Tyrosine-protein kinase Lck

1

3

High-throughput

0.479

High

463514

LYN
Tyrosine-protein kinase Lyn

1

3

High-throughput

0.479

High

466246

RHOC
Rho-related GTP-binding protein RhoC

1

12

High-throughput

0.479

High

540450

LAMP1
Lysosome-associated membrane glycoprotein 1

1

5

High-throughput

0.479

High

541481

FGFR1
Fibroblast growth factor receptor 1

1

4

High-throughput

0.479

High

562051

LAMP2
Lysosome-associated membrane glycoprotein 2

1

5

High-throughput

0.479

High

581040

RAC2
Ras-related C3 botulinum toxin substrate 2

1

12

High-throughput

0.479

High

601285

RHOQ
Rho-related GTP-binding protein RhoQ

1

16

High-throughput

0.479

High

603973

CXA1
Gap junction alpha-1 protein

1

5

High-throughput

0.479

High

642860

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

1

High-throughput

0.479

High

715581

MARCS
Myristoylated alanine-rich C-kinase substrate

1

1

High-throughput

0.479

High

720217

UFO
Tyrosine-protein kinase receptor UFO

1

3

Small-scale

0.479

High

845639

MUC18
Cell surface glycoprotein MUC18

1

1

High-throughput

0.479

High

910045

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.479

High

936324

AFAD
Afadin

1

3

High-throughput

0.479

High

953441

RAC3
Ras-related C3 botulinum toxin substrate 3

1

14

High-throughput

0.479

High

955157

CDC42
Cell division control protein 42 homolog

1

16

High-throughput

0.479

High

956290

RAB2A
Ras-related protein Rab-2A

1

4

High-throughput

0.479

High

962038

RHOA
Transforming protein RhoA

1

14

High-throughput

0.479

High

962740

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.479

High

975028

ARF6
ADP-ribosylation factor 6

1

1

High-throughput

0.479

High

976263

RB11A
Ras-related protein Rab-11A

1

1

High-throughput

0.479

High

988359

RAC1
Ras-related C3 botulinum toxin substrate 1

1

14

High-throughput

0.479

High

1004054

CXAR
Coxsackievirus and adenovirus receptor

1

1

High-throughput

0.479

High

1015431

RHOG
Rho-related GTP-binding protein RhoG

1

12

High-throughput

0.479

High

1035609

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.479

High

1041059

CAV1
Caveolin-1

1

1

High-throughput

0.479

High

1122004

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.479

High

1122005

RAB35
Ras-related protein Rab-35

1

3

High-throughput

0.479

High

1122007

RHOH
Rho-related GTP-binding protein RhoH

1

16

High-throughput

0.479

High

1122011

OCLN
Occludin

1

2

High-throughput

0.479

High

1122012

Q4LE69
Phosphatidylinositol 4-kinase alpha

1

6

High-throughput

0.479

High

1122018

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.479

High

1122022

RHOU
Rho-related GTP-binding protein RhoU

1

19

High-throughput

0.479

High

1122024

CXD3
Gap junction delta-3 protein

1

5

High-throughput

0.479

High

1122027

PARD3
Partitioning defective 3 homolog

1

1

High-throughput

0.479

High

1122029

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.479

High

1122035

RHOV
Rho-related GTP-binding protein RhoV

1

16

High-throughput

0.479

High

1122037

PANX1
Pannexin-1

1

1

High-throughput

0.479

High

1122043

DNJC5
DnaJ homolog subfamily C member 5

1

2

High-throughput

0.479

High

1122044

RHOJ
Rho-related GTP-binding protein RhoJ

1

16

High-throughput

0.479

High

1122045

RHOF
Rho-related GTP-binding protein RhoF

1

18

High-throughput

0.479

High

1122050

RNF12
E3 ubiquitin-protein ligase RLIM

1

1

High-throughput

0.479

High

1122052

LAMP3
Lysosome-associated membrane glycoprotein 3

1

5

High-throughput

0.479

High

247323

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

0

High-throughput

0.458

High

556077

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

658962

PTPRE
Receptor-type tyrosine-protein phosphatase epsilon

1

0

High-throughput

0.458

High

1122006

KS6A2
Ribosomal protein S6 kinase alpha-2

1

0

High-throughput

0.458

High

1122008

T22D1
TSC22 domain family protein 1

1

0

High-throughput

0.458

High

1122047

ANLN
Anillin

1

0

High-throughput

0.458

High

1122051

HDAC6
Protein deacetylase HDAC6

1

0

High-throughput

0.458

High

182531

GP182
G-protein coupled receptor 182

1

2

High-throughput

0.445

High

839456

PI4KA
Phosphatidylinositol 4-kinase alpha

1

6

High-throughput

0.445

High

1122023

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

1

High-throughput

0.445

High

327258

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.437

High

330955

KI20A
Kinesin-like protein KIF20A

1

3

High-throughput

0.437

High

1122030

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

1122033

CK052
Uncharacterized protein C11orf52

1

1

High-throughput

0.437

High

1122046

E41LA
Band 4.1-like protein 4A

1

1

High-throughput

0.437

High

538590

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

0

High-throughput

0.426

High

1122041

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.426

High

75564

B3KSW4
Regulator of G protein signaling 20

1

3

High-throughput

0.407

High

1122053

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

2

High-throughput

0.407

High

354016

CX001
Putative transmembrane protein CXorf1

1

0

High-throughput

0.279

Low

505489

ARMS2
Age-related maculopathy susceptibility protein 2

1

0

High-throughput

0.279

Low

848257

MAGA3
Melanoma-associated antigen 3

1

0

High-throughput

0.279

Low

1040614

PO3F1
POU domain, class 3, transcription factor 1

1

0

High-throughput

0.279

Low

1093750

GAGE5
G antigen 5

1

0

High-throughput

0.279

Low

1122020

ZN517
Zinc finger protein 517

1

0

High-throughput

0.279

Low

1122034

ISG20
Interferon-stimulated gene 20 kDa protein

1

0

High-throughput

0.279

Low

1122048

MMP26
Matrix metalloproteinase-26

1

0

High-throughput

0.279

Low

139869

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

0

High-throughput

0.249

Low

247897

NUPR1
Nuclear protein 1

1

0

High-throughput

0.249

Low

1122038

RING2
E3 ubiquitin-protein ligase RING2

1

0

High-throughput

0.249

Low

1122015

BTBD8
BTB/POZ domain-containing protein 8

1

0

High-throughput

0.232

Low

1122021

SAMC
Mitochondrial S-adenosylmethionine carrier protein

1

0

High-throughput

0.232

Low

1122039

ZBT18
Zinc finger and BTB domain-containing protein 18

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025