HitPredict

Interactor 1: NSP1 (P14907)
Nucleoporin NSP1 (Nuclear pore protein NSP1) (Nucleoskeletal-like protein) (p110)
Gene: NSP1

Interactor 2: IMB3 (P32337)
Importin subunit beta-3 (Karyopherin subunit beta-3) (Karyopherin-121) (Protein secretion enhancer 1)
Gene: PSE1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	9891088, 17897934, 22357553
Identification Methods	coimmunoprecipitation, affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006606 - protein import into nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 823 Sc			1 1089
+	Sc
		541885 NSP1_YEAST (1-823): 3.8e-105: 344: 100.00		IMB4_YEAST (7-1076): 8.52e-100: 342: 18.75
+	Sc
		687906 NUP2_YEAST (266-640): 3.09e-19: 94.9: 27.02		IMB3_YEAST (1-1089): 3.51e-179: 555: 100.00
+	Sc
		595002 NUP1_YEAST (127-661): 8.67e-14: 77.6: 19.46		IMB3_YEAST (1-1089): 3.51e-179: 555: 100.00
+	Ce
		136533 O01576_CAEEL (59-822): 2.52e-41: 164: 14.53		Q9N5V3_CAEEL (11-1083): 1.09e-144: 464: 24.30
+	Sc
		541927 NSP1_YEAST (1-823): 3.8e-105: 344: 100.00		IMB1_YEAST (14-701): 1.06e-46: 183: 15.89
+	Sc
		691631 NUP2_YEAST (266-640): 3.09e-19: 94.9: 27.02		IMB4_YEAST (7-1076): 8.52e-100: 342: 18.75
+	Sc
		595034 NUP1_YEAST (127-661): 8.67e-14: 77.6: 19.46		IMB4_YEAST (7-1076): 8.52e-100: 342: 18.75
+	Hs
		727300 NU214_HUMAN (3-480): 1.31e-13: 77.2: 13.84		TNPO1_HUMAN (293-1089): 1.13e-68: 250: 11.87
+	Ce
		248166 P91457_CAEEL (2-473): 5.44e-13: 75.3: 10.17		O62332_CAEEL (246-1088): 2.4e-63: 234: 11.19
+	At
		1226226 NUP62_ARATH (100-821): 3.75e-43: 169: 13.46		IMB1_ARATH (224-965): 3.34e-33: 140: 10.83
+	Xl
		853823 Q91349_XENLA (291-823): 1.42e-55: 202: 21.25		IMB_XENLA (610-1085): 3.64e-15: 82.8: 10.69
+	Sc
		691667 NUP2_YEAST (266-640): 3.09e-19: 94.9: 27.02		IMB1_YEAST (14-701): 1.06e-46: 183: 15.89
+	Hs
		740152 NUP62_HUMAN (301-823): 1.2e-48: 182: 17.11		IMB1_HUMAN (610-1085): 3.63e-16: 85.8: 10.82
+	Sc
		595023 NUP1_YEAST (127-661): 8.67e-14: 77.6: 19.46		IMB2_YEAST (12-589): 3.14e-48: 188: 18.28
+	Sc
		595074 NUP1_YEAST (127-661): 8.67e-14: 77.6: 19.46		IMB1_YEAST (14-701): 1.06e-46: 183: 15.89
+	Xl
		1137359 NU153_XENLA (75-663): 3.6e-15: 82.2: 10.27		Q5U4V0_XENLA (1-626): 1.13e-25: 116: 11.44
+	Hs
		127345 P121A_HUMAN (17-622): 2.27e-19: 95.7: 11.11		IPO5_HUMAN (3-679): 6.25e-18: 91.6: 10.34
+	Hs
		1060869 P121A_HUMAN (17-622): 2.27e-19: 95.7: 11.11		IMB1_HUMAN (610-1085): 3.63e-16: 85.8: 10.82
+	Hs
		127197 NU214_HUMAN (3-480): 1.31e-13: 77.2: 13.84		IPO5_HUMAN (3-679): 6.25e-18: 91.6: 10.34
+	Hs
		727254 NU214_HUMAN (3-480): 1.31e-13: 77.2: 13.84		IMB1_HUMAN (610-1085): 3.63e-16: 85.8: 10.82