HitPredict

Interactor 1: NSP1 (P14907)
Nucleoporin NSP1 (Nuclear pore protein NSP1) (Nucleoskeletal-like protein) (p110)
Gene: NSP1

Interactor 2: NUP57 (P48837)
Nucleoporin NUP57 (Nuclear pore protein NUP57)
Gene: NUP57

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.989

The method score is based on:

Property Details
Experiments 11283351, 7688296, 11387327, 8565072, 10688190, 11689687, 16554755, 16429126, 15741174, 18467557, 33333025, 37968396, 18046405, 24165936, 9017593, 7559750, 22940862, 22875988, 24574455, 27194810
Identification Methods two hybrid pooling approach, coimmunoprecipitation, affinity chromatography technology, two hybrid, protein complementation assay, far western blotting, pull down, biochemical, two hybrid array, dihydrofolate reductase reconstruction and 1 others

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Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Nsp1_C~Nup54
Common GO terms GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore
GO:0006606 - protein import into nucleus
GO:0006607 - NLS-bearing protein import into nucleus
GO:0006913 - nucleocytoplasmic transport
and 3 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 823
Sc

1 541
+ Sc
+ Hs
+ Xl
+ Xl
+ Rn
+ Hs
+ Sc
+ Ce
+ Sc
+ Sc
+ Sc
+ Xl
+ Hs
+ Hs
+ At
+ Ce
+ Ce
+ Dm
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024