HitPredict

Interactor 1: TOP1 (P11387)
DNA topoisomerase 1 (EC 5.6.2.1) (DNA topoisomerase I)
Gene: TOP1

Interactor 2: RUXG (P62308)
Small nuclear ribonucleoprotein G (snRNP-G) (Sm protein G) (Sm-G) (SmG)
Gene: SNRPG

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 765 Hs			1 76
+	Hs
		71557 TOP1_HUMAN (1-765): 0: 952: 100.00		RUXGL_HUMAN (1-76): 7.71e-29: 99.4: 94.74
+	Hs
		541925 TOP1_HUMAN (1-765): 0: 952: 100.00		LSM6_HUMAN (3-75): 3.43e-27: 95.5: 26.03
+	Hs
		541923 TOP1_HUMAN (1-765): 0: 952: 100.00		RUXF_HUMAN (5-73): 4.27e-24: 87.8: 24.64
+	Hs
		541806 TOP1_HUMAN (1-765): 0: 952: 100.00		RSMB_HUMAN (1-70): 6.78e-22: 86.3: 21.25