HitPredict

Interactor 1: CYC8 (P14922)
General transcriptional corepressor CYC8 (Glucose repression mediator protein CYC8)
Gene: CYC8

Interactor 2: HOS2 (P53096)
Probable histone deacetylase HOS2 (EC 3.5.1.98)
Gene: HOS2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.623

Property	Details
Experiments	14525981, 11069890
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 966 Sc			1 452
+	Sc
		542112 CYC8_YEAST (39-966): 3.72e-104: 349: 100.00		RPD3_YEAST (10-439): 0: 546: 44.60
+	Hs
		174859 OGT1_HUMAN (1-317): 7.62e-59: 221: 16.20		HDAC1_HUMAN (22-434): 0: 578: 48.56
+	Ca
		1124248 Q5ADP3_CANAL (2-966): 8.27e-45: 177: 15.97		Q5ADP0_CANAL (18-447): 0: 554: 45.52
+	Hs
		684697 STIP1_HUMAN (1-286): 6.54e-34: 140: 13.94		HDAC1_HUMAN (22-434): 0: 578: 48.56
+	Hs
		684929 STIP1_HUMAN (1-286): 6.54e-34: 140: 13.94		HDAC2_HUMAN (17-447): 0: 574: 45.85
+	Hs
		1038797 CDC23_HUMAN (1-193): 1.63e-24: 111: 13.50		HDAC1_HUMAN (22-434): 0: 578: 48.56
+	Hs
		1270512 CDC23_HUMAN (1-193): 1.63e-24: 111: 13.50		HDAC2_HUMAN (17-447): 0: 574: 45.85
+	Hs
		1038609 TTC28_HUMAN (49-487): 5.46e-13: 75.8: 11.31		HDAC1_HUMAN (22-434): 0: 578: 48.56
+	Mm
		1157700 NAA15_MOUSE (3-599): 2.02e-54: 206: 12.16		HDAC4_MOUSE (2-423): 9.4e-145: 442: 23.09
+	Mm
		102620 G3X8Y3_MOUSE (3-599): 3.8e-54: 205: 12.16		HDAC4_MOUSE (2-423): 9.4e-145: 442: 23.09
+	Hs
		684567 STIP1_HUMAN (1-286): 6.54e-34: 140: 13.94		HDAC4_HUMAN (2-423): 5.68e-141: 432: 22.17
+	Sc
		542159 CYC8_YEAST (39-966): 3.72e-104: 349: 100.00		HOS1_YEAST (110-335): 1.48e-43: 160: 41.30