HitPredict

Interactor 1: PLAK (P14923)
Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)
Gene: JUP

Interactor 2: NTRK3 (Q16288)
NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)
Gene: NTRK3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 745 Hs			1 839
+	Hs
		717118 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		NTRK3_HUMAN (1-839): 0: 671: 100.00
+	Hs
		384204 PLAK_HUMAN (1-745): 0: 551: 100.00		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		507826 PLAK_HUMAN (1-745): 0: 551: 100.00		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		384375 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		507882 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		239141 CTND1_HUMAN (203-728): 3.14e-90: 305: 16.25		NTRK3_HUMAN (1-839): 0: 671: 100.00
+	Hs
		134907 IMA3_HUMAN (228-670): 2.7e-65: 227: 16.01		NTRK3_HUMAN (1-839): 0: 671: 100.00
+	Hs
		434143 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		RET_HUMAN (282-837): 1.5e-108: 360: 25.76
+	Hs
		239021 CTND1_HUMAN (203-728): 3.14e-90: 305: 16.25		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		542283 PLAK_HUMAN (1-745): 0: 551: 100.00		ROR1_HUMAN (509-821): 2.63e-67: 243: 40.50
+	Hs
		435524 PLAK_HUMAN (1-745): 0: 551: 100.00		IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16
+	Mm
		546270 PLAK_MOUSE (1-745): 0: 553: 98.39		INSR_MOUSE (513-824): 2.11e-62: 231: 38.80
+	Hs
		717128 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		DDR2_HUMAN (527-824): 2.05e-70: 250: 43.30
+	Hs
		435557 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16
+	Rn
		544931 CTNB1_RAT (1-731): 1.13e-173: 519: 67.38		INSR_RAT (513-824): 3.31e-62: 230: 38.80
+	Hs
		131365 IMA4_HUMAN (228-670): 5.34e-64: 224: 15.79		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		384530 IMA5_HUMAN (231-685): 6.58e-61: 215: 15.06		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		384529 IMA1_HUMAN (270-664): 6.19e-48: 179: 14.32		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		239027 CTND1_HUMAN (203-728): 3.14e-90: 305: 16.25		RET_HUMAN (282-837): 1.5e-108: 360: 25.76
+	Hs
		717051 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		PTK7_HUMAN (215-380): 9.02e-12: 71.3: 17.34