Interactor 1: TOP2A (P11388)
DNA topoisomerase 2-alpha (EC 5.6.2.2) (DNA topoisomerase II, alpha isozyme)
Gene: TOP2A

Interactor 2: CYLC1 (P35663)
Cylicin-1 (Cylicin I) (Multiple-band polypeptide I)
Gene: CYLC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 35575683
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1531
Hs

1 651
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 11Aug2025