Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.950

The method score is based on:

Property Details
Experiments 11967834, 30869872, 19554567, 37295430, 20159554, 18492664, unassigned1933
Identification Methods unspecified method, pull down, x-ray crystallography, affinity chromatography technology, fluorescent resonance energy transfer, dihydrofolate reductase reconstruction
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HATPase_c_3~HATPase_c_3, HATPase_c_3~HSP90, HSP90~HSP90
Common GO terms GO:0000723 - telomere maintenance
GO:0000492 - box C/D snoRNP assembly
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
and 13 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 705
Sc

1 705
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ At
+ Sc
+ Sc
+ Hs
+ Hs
+ Ca
+ Ce
+ Sp
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024