HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: KPR3 (P38689)
Ribose-phosphate pyrophosphokinase 3 (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthase 3)
Gene: PRS3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	16429126, 37295430
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 320
+	Sc
		543657 HSC82_YEAST (1-705): 0: 977: 100.00		KPR2_YEAST (1-320): 1.06e-162: 457: 62.93
+	Sc
		543582 HSC82_YEAST (1-705): 0: 977: 100.00		KPR4_YEAST (1-320): 3.48e-162: 456: 63.55
+	Sc
		366226 HSP82_YEAST (1-705): 0: 968: 95.63		KPR3_YEAST (1-320): 6.2e-163: 458: 100.00
+	Ca
		804555 HSP90_CANAL (4-705): 0: 953: 82.36		Q5ALK3_CANAL (1-320): 3.05e-164: 461: 86.88
+	Sc
		544602 HSC82_YEAST (1-705): 0: 977: 100.00		KPR5_YEAST (111-201): 1.22e-33: 130: 57.61