HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: AFG3 (P39925)
Mitochondrial inner membrane m-AAA protease component YTA10 (EC 3.4.24.-) (EC 3.6.-.-) (ATPase family gene 3 protein) (Tat-binding homolog 10)
Gene: AFG3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.594

Property	Details
Experiments	11805837, 37295430
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005739 - mitochondrion GO:0016887 - ATP hydrolysis activity
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 761
+	Sc
		366329 HSP82_YEAST (1-705): 0: 968: 95.63		AFG3_YEAST (1-761): 0: 630: 100.00
+	Sc
		543849 HSC82_YEAST (1-705): 0: 977: 100.00		YTA12_YEAST (22-747): 3.09e-167: 504: 52.52
+	Sc
		366385 HSP82_YEAST (1-705): 0: 968: 95.63		YTA12_YEAST (22-747): 3.09e-167: 504: 52.52
+	Sc
		543430 HSC82_YEAST (1-705): 0: 977: 100.00		YME1_YEAST (64-755): 1.19e-131: 410: 27.79
+	Sc
		543294 HSC82_YEAST (1-705): 0: 977: 100.00		CDC48_YEAST (87-555): 5.82e-101: 331: 24.24
+	Sc
		365885 HSP82_YEAST (1-705): 0: 968: 95.63		CDC48_YEAST (87-555): 5.82e-101: 331: 24.24