HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: PRS4 (P40327)
26S proteasome regulatory subunit 4 homolog (Tat-binding homolog 5)
Gene: RPT2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31399574, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0016887 - ATP hydrolysis activity
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 437
+	At
		137806 HS904_ARATH (3-705): 0: 991: 63.37		PRS4A_ARATH (1-437): 7.3e-132: 388: 68.85
+	Sc
		366381 HSP82_YEAST (1-705): 0: 968: 95.63		PRS4_YEAST (1-437): 1.18e-134: 395: 100.00
+	Sc
		543462 HSC82_YEAST (1-705): 0: 977: 100.00		PRS6B_YEAST (57-419): 9.33e-112: 337: 48.77
+	Sc
		366044 HSP82_YEAST (1-705): 0: 968: 95.63		PRS6B_YEAST (57-419): 9.33e-112: 337: 48.77
+	Sc
		544264 HSC82_YEAST (1-705): 0: 977: 100.00		PRS8_YEAST (106-429): 1.25e-104: 318: 49.38
+	Sc
		366752 HSP82_YEAST (1-705): 0: 968: 95.63		PRS8_YEAST (106-429): 1.25e-104: 318: 49.38
+	Ca
		804504 HSP90_CANAL (4-705): 0: 953: 82.36		Q5A0L8_CANAL (87-436): 1.33e-110: 333: 50.14