HitPredict

Interactor 1: INSR (P15127)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Interactor 2: COPG1 (Q4AEF8)
Coatomer subunit gamma-1 (Gamma-1-coat protein) (Gamma-1-COP)
Gene: COPG1

Species: Rattus norvegicus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	30300385
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005198 - structural molecule activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1383 Rn			1 874
+	Rn
		102587 INSR_RAT (1-1383): 0: 1575: 100.00		G3V9N8_RAT (14-872): 0: 676: 13.56
+	Rn
		71352 INSR_RAT (1-1383): 0: 1575: 100.00		B2RYN6_RAT (20-741): 7.95e-175: 528: 14.97
+	Hs
		665549 EPHA8_HUMAN (663-1323): 1.14e-174: 548: 22.59		COPG1_HUMAN (1-874): 0: 852: 97.14
+	Hs
		665540 EPHA8_HUMAN (663-1323): 1.14e-174: 548: 22.59		COPG2_HUMAN (1-874): 0: 838: 80.66
+	Hs
		665202 EPHA2_HUMAN (662-1321): 2.76e-167: 528: 22.70		AP2B1_HUMAN (14-871): 0: 669: 13.97
+	Hs
		321491 EPHA2_HUMAN (662-1321): 2.76e-167: 528: 22.70		AP2A1_HUMAN (24-874): 0: 617: 14.46
+	Hs
		385808 NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95		COPG1_HUMAN (1-874): 0: 852: 97.14
+	Hs
		385654 NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95		COPG2_HUMAN (1-874): 0: 838: 80.66
+	Hs
		384621 NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95		AP2B1_HUMAN (14-871): 0: 669: 13.97
+	Hs
		1014018 NTRK2_HUMAN (997-1293): 1.8e-67: 246: 42.72		AP1B1_HUMAN (14-872): 0: 661: 13.68
+	Hs
		384728 NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95		AP1B1_HUMAN (14-872): 0: 661: 13.68
+	Hs
		321460 NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95		AP2A1_HUMAN (24-874): 0: 617: 14.46
+	Hs
		321487 FGFR3_HUMAN (1016-1288): 2.88e-60: 224: 40.07		AP2A1_HUMAN (24-874): 0: 617: 14.46
+	Hs
		302086 NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95		AP2A2_HUMAN (24-874): 0: 597: 15.46
+	Hs
		338254 EGFR_HUMAN (32-308): 1.21e-29: 130: 22.50		AP2B1_HUMAN (14-871): 0: 669: 13.97
+	Hs
		338339 EGFR_HUMAN (32-308): 1.21e-29: 130: 22.50		AP1B1_HUMAN (14-872): 0: 661: 13.68
+	Hs
		212583 NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95		AP1G1_HUMAN (20-741): 3.44e-175: 529: 15.09
+	Hs
		321451 EGFR_HUMAN (32-308): 1.21e-29: 130: 22.50		AP2A1_HUMAN (24-874): 0: 617: 14.46
+	Hs
		302078 EGFR_HUMAN (32-308): 1.21e-29: 130: 22.50		AP2A2_HUMAN (24-874): 0: 597: 15.46
+	Hs
		212580 EGFR_HUMAN (32-308): 1.21e-29: 130: 22.50		AP1G1_HUMAN (20-741): 3.44e-175: 529: 15.09