HitPredict

Interactor 1: PVR (P15151)
Poliovirus receptor (Nectin-like protein 5) (NECL-5) (CD antigen CD155)
Gene: PVR

Interactor 2: SLAF8 (Q9P0V8)
SLAM family member 8 (B-lymphocyte activator macrophage expressed) (BCM-like membrane protein) (CD antigen CD353)
Gene: SLAMF8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0009986 - cell surface GO:0016020 - membrane GO:0038023 - signaling receptor activity
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 417 Hs			1 285
+	Hs
		545117 PVR_HUMAN (1-417): 3.29e-84: 265: 100.00		CEA21_HUMAN (5-279): 1.42e-49: 167: 15.88
+	Hs
		1108799 NECT2_HUMAN (25-333): 4.43e-71: 234: 52.80		CEA21_HUMAN (5-279): 1.42e-49: 167: 15.88
+	Hs
		1108793 CADM4_HUMAN (1-395): 3.16e-61: 204: 20.50		CEA21_HUMAN (5-279): 1.42e-49: 167: 15.88
+	Hs
		940514 NECT2_HUMAN (25-333): 4.43e-71: 234: 52.80		CXAR_HUMAN (1-270): 5.84e-35: 131: 16.26
+	Hs
		962538 PSG4_HUMAN (4-414): 5.59e-63: 210: 16.39		PSG8_HUMAN (7-228): 1.44e-19: 89.5: 14.80
+	Hs
		509865 PSG1_HUMAN (4-414): 2.92e-62: 208: 17.10		PSG5_HUMAN (7-231): 2.37e-20: 91: 14.22
+	Hs
		509889 PSG1_HUMAN (4-414): 2.92e-62: 208: 17.10		PSG8_HUMAN (7-228): 1.44e-19: 89.5: 14.80
+	Hs
		962537 PSG4_HUMAN (4-414): 5.59e-63: 210: 16.39		PSG11_HUMAN (7-224): 5.31e-19: 87.2: 11.87
+	Hs
		962534 PSG4_HUMAN (4-414): 5.59e-63: 210: 16.39		PSG3_HUMAN (8-224): 2.79e-18: 86: 14.29
+	Hs
		509860 PSG4_HUMAN (4-414): 5.59e-63: 210: 16.39		PSG1_HUMAN (8-220): 1.39e-17: 84.1: 14.95
+	Hs
		509867 PSG1_HUMAN (4-414): 2.92e-62: 208: 17.10		PSG3_HUMAN (8-224): 2.79e-18: 86: 14.29
+	Hs
		509861 PSG1_HUMAN (4-414): 2.92e-62: 208: 17.10		PSG6_HUMAN (8-229): 2.68e-17: 83.3: 15.32
+	Hs
		962523 PSG9_HUMAN (4-415): 1.6e-59: 201: 16.11		PSG3_HUMAN (8-224): 2.79e-18: 86: 14.29
+	Hs
		509859 PSG1_HUMAN (4-414): 2.92e-62: 208: 17.10		PSG9_HUMAN (8-229): 8.42e-16: 78.7: 15.04
+	Hs
		1018295 CNTN1_HUMAN (122-417): 5.21e-28: 118: 12.58		CEA21_HUMAN (5-279): 1.42e-49: 167: 15.88
+	Hs
		68238 CADM4_HUMAN (1-395): 3.16e-61: 204: 20.50		HECA2_HUMAN (17-282): 2.4e-15: 77.5: 14.91
+	Mm
		1149039 CNTN4_MOUSE (145-417): 1.02e-29: 123: 13.33		CNTN4_MOUSE (125-244): 6.67e-12: 67.5: 15.57