HitPredict

Interactor 1: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Interactor 2: NCPR (P16435)
NADPH--cytochrome P450 reductase (CPR) (P450R) (EC 1.6.2.4)
Gene: POR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 677
+	Hs
		560186 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		NCPR_HUMAN (1-677): 0: 975: 100.00
+	Hs
		560181 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		NCPR_HUMAN (1-677): 0: 975: 100.00
+	Hs
		560188 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		NCPR_HUMAN (1-677): 0: 975: 100.00
+	Hs
		560182 CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75		NCPR_HUMAN (1-677): 0: 975: 100.00
+	Hs
		560184 RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26		NCPR_HUMAN (1-677): 0: 975: 100.00
+	Hs
		436146 RHOC_HUMAN (5-192): 1.83e-73: 221: 54.79		NCPR_HUMAN (1-677): 0: 975: 100.00
+	Hs
		718483 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		NOS2_HUMAN (44-676): 0: 694: 29.68
+	Hs
		545231 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		NOS2_HUMAN (44-676): 0: 694: 29.68
+	Mm
		667784 RAC1_MOUSE (1-192): 1.69e-84: 249: 92.19		NOS2_MOUSE (65-676): 0: 685: 29.44
+	Mm
		667792 RAC2_MOUSE (1-192): 2.41e-82: 243: 98.96		NOS2_MOUSE (65-676): 0: 685: 29.44
+	Hs
		545647 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		TYW1_HUMAN (82-223): 4.14e-23: 106: 40.39
+	Hs
		951387 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		TYW1_HUMAN (82-223): 4.14e-23: 106: 40.39
+	Hs
		894493 CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75		TYW1_HUMAN (82-223): 4.14e-23: 106: 40.39
+	Hs
		900962 RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26		TYW1_HUMAN (82-223): 4.14e-23: 106: 40.39