HitPredict

Interactor 1: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Interactor 2: ITA6 (P23229)
Integrin alpha-6 (CD49 antigen-like family member F) (VLA-6) (CD antigen CD49f) [Cleaved into: Integrin alpha-6 heavy chain; Integrin alpha-6 light chain; Processed integrin alpha-6 (Alpha6p)]
Gene: ITGA6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005925 - focal adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 1130
+	Hs
		613239 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		ITA6_HUMAN (1-1130): 0: 1347: 100.00
+	Hs
		564413 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		ITA6_HUMAN (1-1130): 0: 1347: 100.00
+	Hs
		613231 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		ITA6_HUMAN (1-1130): 0: 1347: 100.00
+	Hs
		639881 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		ITA3_HUMAN (7-1108): 0: 936: 34.72
+	Hs
		419189 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		ITAV_HUMAN (21-1083): 0: 880: 25.14
+	Hs
		419150 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		ITAV_HUMAN (21-1083): 0: 880: 25.14
+	Hs
		419149 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		ITAV_HUMAN (21-1083): 0: 880: 25.14
+	Hs
		419184 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		ITAV_HUMAN (21-1083): 0: 880: 25.14
+	Hs
		530601 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		ITA4_HUMAN (2-1096): 0: 865: 23.40
+	Hs
		530400 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		ITA4_HUMAN (2-1096): 0: 865: 23.40
+	Hs
		443068 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		ITA5_HUMAN (21-1086): 0: 855: 25.09
+	Hs
		443030 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		ITA5_HUMAN (21-1086): 0: 855: 25.09
+	Hs
		443028 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		ITA5_HUMAN (21-1086): 0: 855: 25.09
+	Hs
		443059 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		ITA5_HUMAN (21-1086): 0: 855: 25.09
+	Hs
		880211 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		ITA1_HUMAN (161-1090): 0: 646: 21.01
+	Hs
		564464 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		ITA1_HUMAN (161-1090): 0: 646: 21.01
+	Hs
		545290 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		ITA1_HUMAN (161-1090): 0: 646: 21.01
+	Hs
		566873 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		ITA2_HUMAN (20-494): 2.1e-34: 145: 15.22
+	Hs
		564407 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		ITA2_HUMAN (20-494): 2.1e-34: 145: 15.22
+	Hs
		566865 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		ITA2_HUMAN (20-494): 2.1e-34: 145: 15.22