HitPredict

Interactor 1: ERF3A (P15170)
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Eukaryotic peptide chain release factor subunit 3a) (eRF3a) (EC 3.6.5.-) (G1 to S phase transition protein 1 homolog)
Gene: GSPT1

Interactor 2: P85A (P27986)
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)
Gene: PIK3R1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	21988832
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 499 Hs			1 724
+	Hs
		129272 EF1A1_HUMAN (70-498): 1.24e-175: 503: 38.29		P85B_HUMAN (4-719): 6.38e-162: 486: 57.24
+	Hs
		545883 ERF3A_HUMAN (1-499): 0: 567: 100.00		RHG24_HUMAN (94-443): 7.45e-57: 208: 16.76
+	Hs
		545912 ERF3A_HUMAN (1-499): 0: 567: 100.00		RHG23_HUMAN (40-369): 2.83e-52: 198: 16.80
+	Hs
		932780 EF1A1_HUMAN (70-498): 1.24e-175: 503: 38.29		RHG24_HUMAN (94-443): 7.45e-57: 208: 16.76