HitPredict

Interactor 1: MYOG (P15173)
Myogenin (Class C basic helix-loop-helix protein 3) (bHLHc3) (Myogenic factor 4) (Myf-4)
Gene: MYOG

Interactor 2: ID4 (P47928)
DNA-binding protein inhibitor ID-4 (Class B basic helix-loop-helix protein 27) (bHLHb27) (Inhibitor of DNA binding 4) (Inhibitor of differentiation 4)
Gene: ID4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0046983 - protein dimerization activity
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 224 Hs			1 161
+	Hs
		546071 MYOG_HUMAN (1-224): 7.77e-76: 230: 100.00		ID1_HUMAN (12-161): 1.12e-51: 163: 37.42
+	Hs
		616610 MYF6_HUMAN (1-222): 5.25e-52: 170: 43.50		ID4_HUMAN (1-161): 1.67e-63: 194: 100.00
+	Hs
		526742 MYF5_HUMAN (4-219): 7.48e-59: 187: 40.00		ID1_HUMAN (12-161): 1.12e-51: 163: 37.42
+	Mm
		485951 MYOD1_MOUSE (4-212): 6.95e-50: 166: 35.42		Q6GTZ3_MOUSE (35-161): 2e-51: 162: 39.39
+	Hs
		526743 MYF5_HUMAN (4-219): 7.48e-59: 187: 40.00		ID2_HUMAN (1-148): 2.51e-41: 136: 43.24
+	Hs
		545945 MYOD1_HUMAN (4-216): 3.41e-45: 154: 34.15		ID1_HUMAN (12-161): 1.12e-51: 163: 37.42
+	Mm
		485939 MYOD1_MOUSE (4-212): 6.95e-50: 166: 35.42		ID2_MOUSE (1-148): 1.17e-41: 137: 42.57
+	Hs
		526744 MYF5_HUMAN (4-219): 7.48e-59: 187: 40.00		ID3_HUMAN (1-135): 2.13e-33: 116: 44.44
+	Hs
		814916 NGN3_HUMAN (12-202): 5.77e-28: 107: 19.69		ID4_HUMAN (1-161): 1.67e-63: 194: 100.00
+	Hs
		524549 LYL1_HUMAN (48-195): 4.71e-27: 106: 21.48		ID4_HUMAN (1-161): 1.67e-63: 194: 100.00
+	Hs
		545958 MYOD1_HUMAN (4-216): 3.41e-45: 154: 34.15		ID2_HUMAN (1-148): 2.51e-41: 136: 43.24
+	Hs
		814909 FIGLA_HUMAN (78-176): 5.76e-22: 91.5: 31.00		ID4_HUMAN (1-161): 1.67e-63: 194: 100.00
+	Mm
		485938 MYOD1_MOUSE (4-212): 6.95e-50: 166: 35.42		ID3_MOUSE (1-135): 2.97e-32: 113: 42.96
+	Hs
		780971 ASCL4_HUMAN (47-164): 5.84e-32: 116: 30.23		ID1_HUMAN (12-161): 1.12e-51: 163: 37.42
+	Hs
		545959 MYOD1_HUMAN (4-216): 3.41e-45: 154: 34.15		ID3_HUMAN (1-135): 2.13e-33: 116: 44.44
+	Hs
		524547 LYL1_HUMAN (48-195): 4.71e-27: 106: 21.48		ID1_HUMAN (12-161): 1.12e-51: 163: 37.42
+	Hs
		970583 ASCL4_HUMAN (47-164): 5.84e-32: 116: 30.23		ID2_HUMAN (1-148): 2.51e-41: 136: 43.24
+	Hs
		524557 LYL1_HUMAN (48-195): 4.71e-27: 106: 21.48		ID3_HUMAN (1-135): 2.13e-33: 116: 44.44
+	Dm
		485922 AST4_DROME (76-144): 6.74e-19: 85.3: 33.33		EMC_DROME (67-115): 6.12e-18: 78.5: 55.10