Protein: RPN4
Protein RPN4 (Nuclear protein SON1) (Ubiquitin fusion degradation protein 5)

Gene: RPN4
Organism: Saccharomyces cerevisiae S288C
Interactions: 26
UniProt ID: Q03465

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1042831

UBR2
E3 ubiquitin-protein ligase UBR2

4

0

Small-scale

0.671

High

750999

PRS7
26S proteasome regulatory subunit 7 homolog

2

1

Small-scale

0.584

High

740213

RPN2
26S proteasome regulatory subunit RPN2

2

0

Small-scale

0.582

High

826321

PSMD9
Probable 26S proteasome regulatory subunit p27

2

0

High-throughput

0.565

High

738334

RPN12
26S proteasome regulatory subunit RPN12

2

0

Small-scale

0.559

High

806807

RPN10
26S proteasome regulatory subunit RPN10

2

0

Small-scale

0.559

High

819646

SSB2
Ribosome-associated molecular chaperone SSB2

2

1

High-throughput

0.552

High

662055

PSB6
Proteasome subunit beta type-6

1

0

Small-scale

0.518

High

1041487

MUB1
MYND-type zinc finger protein MUB1

1

0

Small-scale

0.505

High

1039022

IMA1
Importin subunit alpha

1

0

Small-scale

0.504

High

665201

DPB2
DNA polymerase epsilon subunit B

1

0

High-throughput

0.493

High

750887

PRS6B
26S proteasome regulatory subunit 6B homolog

1

1

Small-scale

0.479

High

822430

PRS4
26S proteasome regulatory subunit 4 homolog

1

2

Small-scale

0.479

High

1033877

PRS8
26S proteasome regulatory subunit 8 homolog

1

2

Small-scale

0.479

High

1042833

RPN5
26S proteasome regulatory subunit RPN5

1

1

Small-scale

0.479

High

314905

SEM1
26S proteasome complex subunit SEM1

1

0

Small-scale

0.458

High

750768

PRS6A
26S proteasome regulatory subunit 6A

1

0

Small-scale

0.458

High

865728

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

925015

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

1042832

ESA1
Histone acetyltransferase ESA1

1

0

Small-scale

0.458

High

524980

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

527546

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

546072

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

742279

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

721274

PSB5
Proteasome subunit beta type-5

1

0

Small-scale

0.426

High

1042834

RPN6
26S proteasome regulatory subunit RPN6

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025