HitPredict

Interactor 1: INSR (P15208)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Interactor 2: GRB10 (Q60760)
Growth factor receptor-bound protein 10 (GRB10 adapter protein) (Maternally expressed gene 1 protein)
Gene: GRB10

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.61 1.00 0.786

The method score is based on:

Property Details
Experiments 9062339, 8621530
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation, two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~fn3, BPS~PK_Tyr_Ser-Thr, PH~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH2
Common GO terms GO:0008286 - insulin receptor signaling pathway
GO:0042327 - positive regulation of phosphorylation
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1372
Mm

1 621
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024