Protein: SYG
Glycine--tRNA ligase 1, mitochondrial (EC 6.1.1.14) (Diadenosine tetraphosphate synthetase) (Ap4A synthetase) (EC 2.7.7.-) (Glycyl-tRNA synthetase 1) (GlyRS 1) (GlyRS1)

Gene: SYG, GRS1
Organism: Saccharomyces cerevisiae S288C
Interactions: 91
UniProt ID: P38088

Gene Ontology (top 5):
GO:0004820 - glycine-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

388972

SYTC
Threonine--tRNA ligase, cytoplasmic

1

9

High-throughput

0.618

High

425075

SYH
Histidine--tRNA ligase, mitochondrial

1

2

High-throughput

0.618

High

744038

YHI0
Putative proline--tRNA ligase YHR020W

1

9

High-throughput

0.618

High

744070

SYG2
Glycine--tRNA ligase 2

1

9

High-throughput

0.618

High

680639

HS104
Heat shock protein 104

2

4

Small-scale

0.584

High

744051

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

3

High-throughput

0.584

High

744076

RRP6
Exosome complex exonuclease RRP6

2

3

High-throughput

0.558

High

744077

HRT3
F-box protein HRT3

1

0

Small-scale

0.549

High

744044

RV167
Reduced viability upon starvation protein 167

1

10

High-throughput

0.536

High

744050

EMW1
Essential for maintenance of the cell wall protein 1

1

2

High-throughput

0.536

High

744062

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

3

High-throughput

0.536

High

744069

MAG2
E3 ubiquitin-protein ligase MAG2

1

0

High-throughput

0.513

High

744036

KSP1
Serine/threonine-protein kinase KSP1

1

2

High-throughput

0.501

High

586394

PRP6
Pre-mRNA-splicing factor 6

1

1

High-throughput

0.489

High

701203

SUI1
Eukaryotic translation initiation factor eIF-1

1

1

High-throughput

0.489

High

744056

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

1

High-throughput

0.489

High

343823

SYMC
Methionine--tRNA ligase, cytoplasmic

1

13

High-throughput

0.479

High

366157

HSP82
ATP-dependent molecular chaperone HSP82

1

8

High-throughput

0.479

High

367977

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.479

High

389079

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

10

High-throughput

0.479

High

406990

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.479

High

407870

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

423828

ATPA
ATP synthase subunit alpha, mitochondrial

1

1

High-throughput

0.479

High

482224

RS18A
Small ribosomal subunit protein uS13A

1

3

High-throughput

0.479

High

511016

SSB1
Ribosome-associated molecular chaperone SSB1

1

6

High-throughput

0.479

High

524267

CAF20
Cap-associated protein CAF20

1

2

High-throughput

0.479

High

526334

SYQ
Glutamine--tRNA ligase

1

6

High-throughput

0.479

High

543592

HSC82
ATP-dependent molecular chaperone HSC82

1

8

High-throughput

0.479

High

546166

SYKC
Lysine--tRNA ligase, cytoplasmic

1

10

High-throughput

0.479

High

558018

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

Small-scale

0.479

High

615258

IF5A1
Eukaryotic translation initiation factor 5A-1

1

4

High-throughput

0.479

High

629242

RBSK
Ribokinase

1

1

High-throughput

0.479

High

631828

RS2
Small ribosomal subunit protein uS5

1

3

High-throughput

0.479

High

643664

SYLC
Leucine--tRNA ligase, cytoplasmic

1

13

High-throughput

0.479

High

699872

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

1

High-throughput

0.479

High

703595

PRS6A
26S proteasome regulatory subunit 6A

1

3

High-throughput

0.479

High

729866

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.479

High

730616

EF1G2
Elongation factor 1-gamma 2

1

3

High-throughput

0.479

High

744037

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

10

High-throughput

0.479

High

744039

RPN1
26S proteasome regulatory subunit RPN1

1

3

High-throughput

0.479

High

744042

DHH1
ATP-dependent RNA helicase DHH1

1

3

High-throughput

0.479

High

744049

MMM1
Maintenance of mitochondrial morphology protein 1

1

1

High-throughput

0.479

High

744052

LSB3
LAS seventeen-binding protein 3

1

7

High-throughput

0.479

High

744054

HOSC
Homocitrate synthase, cytosolic isozyme

1

3

High-throughput

0.479

High

744057

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

2

High-throughput

0.479

High

744059

SPC98
Spindle pole body component SPC98

1

2

High-throughput

0.479

High

744060

PPID
Peptidyl-prolyl cis-trans isomerase CPR6

1

2

High-throughput

0.479

High

744061

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.479

High

744067

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

2

High-throughput

0.479

High

744073

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.479

High

744074

TIM18
Mitochondrial import inner membrane translocase subunit TIM18

1

1

High-throughput

0.479

High

744078

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.479

High

627946

SIS1
Protein SIS1

1

3

High-throughput

0.470

High

357262

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.458

High

580896

IRA2
Inhibitory regulator protein IRA2

1

0

Small-scale

0.458

High

605983

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.458

High

698775

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

733653

LAS1
Protein LAS1

1

0

Small-scale

0.458

High

744045

YEY6
MYG1 protein YER156C

1

0

Small-scale

0.458

High

690073

APE2
Aminopeptidase 2, mitochondrial

1

1

High-throughput

0.445

High

715317

SPT7
Transcriptional activator SPT7

1

1

High-throughput

0.445

High

744046

SSB2
Ribosome-associated molecular chaperone SSB2

1

6

High-throughput

0.445

High

744072

SSK1
Osmolarity two-component system protein SSK1

1

2

High-throughput

0.445

High

744047

ULP2
Ubiquitin-like-specific protease 2

1

1

High-throughput

0.439

High

744064

ULP1
Ubiquitin-like-specific protease 1

1

1

High-throughput

0.439

High

413462

RS14A
Small ribosomal subunit protein uS11A

1

2

High-throughput

0.437

High

471012

RS22A
Small ribosomal subunit protein uS8A

1

2

High-throughput

0.437

High

480625

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.437

High

581103

IF5A2
Eukaryotic translation initiation factor 5A-2

1

4

High-throughput

0.437

High

661997

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

689616

MET4
Transcriptional activator of sulfur metabolism MET4

1

2

High-throughput

0.437

High

706226

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.437

High

744035

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

744040

RPN10
26S proteasome regulatory subunit RPN10

1

2

High-throughput

0.437

High

744043

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.437

High

744048

RLP7
Ribosome biogenesis protein RLP7

1

1

High-throughput

0.437

High

744055

VATG
V-type proton ATPase subunit G

1

2

High-throughput

0.437

High

744066

YMC0
Uncharacterized protein YML020W

1

2

High-throughput

0.437

High

744068

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

744071

NVJ2
Nucleus-vacuole junction protein 2

1

1

High-throughput

0.437

High

744075

AP3D
AP-3 complex subunit delta

1

2

High-throughput

0.437

High

744079

RKM4
Ribosomal lysine N-methyltransferase 4

1

1

High-throughput

0.437

High

561235

APA1
Protein APA1 [Includes: Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase 1

1

0

High-throughput

0.426

High

744034

TAF5
Transcription initiation factor TFIID subunit 5

1

4

High-throughput

0.407

High

744065

GCN5
Histone acetyltransferase GCN5

1

2

High-throughput

0.407

High

710872

URB1
Nucleolar pre-ribosomal-associated protein 1

1

0

High-throughput

0.249

Low

732273

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

0

High-throughput

0.249

Low

744058

UTP8
U3 small nucleolar RNA-associated protein 8

1

0

Small-scale

0.249

Low

744041

SPT8
Transcription factor SPT8

1

0

High-throughput

0.232

Low

744053

GWT1
GPI-anchored wall transfer protein 1

1

0

High-throughput

0.232

Low

744063

ADA2
Transcriptional adapter 2

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024