HitPredict - High confidence protein-protein interactions

Interactor 1: B4GT1 (P15291)
Beta-1,4-galactosyltransferase 1 (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (EC 2.4.1.-) (Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase) (Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase) (EC 2.4.1.38) (Lactose synthase A protein) (EC 2.4.1.22) (N-acetyllactosamine synthase) (EC 2.4.1.90) (Nal synthase) (Neolactotriaosylceramide beta-1,4-galactosyltransferase) (EC 2.4.1.275) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1) [Cleaved into: Processed beta-1,4-galactosyltransferase 1]
Gene: B4GALT1

Interactor 2: B4GT1 (P15291)
Beta-1,4-galactosyltransferase 1 (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (EC 2.4.1.-) (Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase) (Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase) (EC 2.4.1.38) (Lactose synthase A protein) (EC 2.4.1.22) (N-acetyllactosamine synthase) (EC 2.4.1.90) (Nal synthase) (Neolactotriaosylceramide beta-1,4-galactosyltransferase) (EC 2.4.1.275) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1) [Cleaved into: Processed beta-1,4-galactosyltransferase 1]
Gene: B4GALT1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	7744867
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Glyco_transf_7C~Glyco_transf_7C, Glyco_transf_7C~Glyco_transf_7N, Glyco_transf_7N~Glyco_transf_7N
Common GO terms	GO:0000138 - Golgi trans cisterna GO:0000139 - Golgi membrane GO:0002064 - epithelial cell development GO:0002526 - acute inflammatory response GO:0003831 - beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity and 40 others more... GO:0003945 - N-acetyllactosamine synthase activity GO:0004461 - lactose synthase activity GO:0005615 - extracellular space GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane GO:0005989 - lactose biosynthetic process GO:0006012 - galactose metabolic process GO:0006487 - protein N-linked glycosylation GO:0006629 - lipid metabolic process GO:0007155 - cell adhesion GO:0007339 - binding of sperm to zona pellucida GO:0007341 - penetration of zona pellucida GO:0008092 - cytoskeletal protein binding GO:0008378 - galactosyltransferase activity GO:0009312 - oligosaccharide biosynthetic process GO:0009897 - external side of plasma membrane GO:0016020 - membrane GO:0016323 - basolateral plasma membrane GO:0030057 - desmosome GO:0030145 - manganese ion binding GO:0030175 - filopodium GO:0030198 - extracellular matrix organization GO:0030667 - secretory granule membrane GO:0031526 - brush border membrane GO:0032580 - Golgi cisterna membrane GO:0032991 - protein-containing complex GO:0035250 - UDP-galactosyltransferase activity GO:0035577 - azurophil granule membrane GO:0043014 - alpha-tubulin binding GO:0043065 - positive regulation of apoptotic process GO:0045136 - development of secondary sexual characteristics GO:0048487 - beta-tubulin binding GO:0050673 - epithelial cell proliferation GO:0050680 - negative regulation of epithelial cell proliferation GO:0060046 - regulation of acrosome reaction GO:0060054 - positive regulation of epithelial cell proliferation involved in wound healing GO:0060055 - angiogenesis involved in wound healing GO:0061755 - positive regulation of circulating fibrinogen levels GO:0070062 - extracellular exosome GO:1905517 - macrophage migration
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	398
Hs

1	398

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Last updated: 15 Jul 2024