HitPredict

Interactor 1: SEC23 (P15303)
Protein transport protein SEC23
Gene: SEC23

Interactor 2: SEC31 (P38968)
Protein transport protein SEC31 (Protein WEB1)
Gene: SEC31

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	1.00	0.927

The method score is based on:

Property	Details
Experiments	9325247, 11805826, 23904270, 22300850, 16429126
Identification Methods	two hybrid, affinity chromatography technology, tandem affinity purification, pull down
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	Gelsolin~Sec31, Sec23_BS~Sec31, Sec23_trunk~Sec31
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0006886 - intracellular protein transport GO:0030127 - COPII vesicle coat GO:0070863 - positive regulation of protein exit from endoplasmic reticulum and 3 others more... GO:0070971 - endoplasmic reticulum exit site GO:0090110 - COPII-coated vesicle cargo loading GO:1902953 - positive regulation of ER to Golgi vesicle-mediated transport
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1	768
Sc

1	1273

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024