Protein: PUS1
tRNA pseudouridine synthase 1 (EC 5.4.99.-) (tRNA pseudouridylate synthase 1) (tRNA-uridine isomerase 1)

Gene: PUS1
Organism: Saccharomyces cerevisiae S288C
Interactions: 48
UniProt ID: Q12211

Gene Ontology (top 5):
GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006397 - mRNA processing
GO:0006400 - tRNA modification

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1084607

PUS1
tRNA pseudouridine synthase 1

1

1

High-throughput

0.665

High

820115

SSB2
Ribosome-associated molecular chaperone SSB2

2

2

High-throughput

0.601

High

918858

UTP22
U3 small nucleolar RNA-associated protein 22

2

0

High-throughput

0.563

High

546735

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.536

High

916929

TAN1
tRNA acetyltransferase TAN1

1

1

High-throughput

0.515

High

646570

RAD53
Serine/threonine-protein kinase RAD53

1

2

Small-scale

0.501

High

1038120

ULP1
Ubiquitin-like-specific protease 1

1

1

High-throughput

0.481

High

671241

SIS1
Protein SIS1

1

1

High-throughput

0.479

High

708524

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

710039

BMH1
Protein BMH1

1

3

High-throughput

0.479

High

925136

APJ1
J domain-containing protein APJ1

1

2

High-throughput

0.479

High

1084417

RRP6
Exosome complex exonuclease RRP6

1

1

High-throughput

0.479

High

740316

PAH1
Phosphatidic acid phosphohydrolase 1

1

0

Small-scale

0.460

High

594636

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

735229

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

825716

SPO22
Sporulation-specific protein 22

1

0

Small-scale

0.458

High

1044506

RUVB1
RuvB-like protein 1

1

0

High-throughput

0.458

High

1051623

HRQ1
ATP-dependent helicase HRQ1

1

0

Small-scale

0.458

High

1084278

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

745059

YSC84
Protein YSC84

1

1

High-throughput

0.457

High

850505

LSB3
LAS seventeen-binding protein 3

1

1

High-throughput

0.457

High

393520

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.445

High

742671

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

811434

CAJ1
Protein CAJ1

1

2

High-throughput

0.445

High

893180

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

1

2

High-throughput

0.445

High

805723

YHS2
MIP18 family protein YHR122W

1

0

High-throughput

0.438

High

150013

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.426

High

435435

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.426

High

684884

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.426

High

885117

RL4B
Large ribosomal subunit protein uL4B

1

0

High-throughput

0.426

High

1050209

RRP5
rRNA biogenesis protein RRP5

1

0

High-throughput

0.426

High

671739

SCJ1
DnaJ-related protein SCJ1

1

1

High-throughput

0.407

High

826513

DJP1
DnaJ-like protein 1

1

2

High-throughput

0.407

High

863784

PFD1
Prefoldin subunit 1

1

1

High-throughput

0.407

High

1065534

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.269

Low

1084608

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.249

Low

383948

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.232

Low

410395

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.232

Low

427486

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.232

Low

432737

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.232

Low

433091

RL6B
Large ribosomal subunit protein eL6B

1

0

High-throughput

0.232

Low

511872

RS24A
Small ribosomal subunit protein eS24A

1

0

High-throughput

0.232

Low

569884

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.232

Low

570188

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.232

Low

712699

RL8B
Large ribosomal subunit protein eL8B

1

0

High-throughput

0.232

Low

752883

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

753653

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025