HitPredict

Interactor 1: EZRI (P15311)
Ezrin (Cytovillin) (Villin-2) (p81)
Gene: EZR

Interactor 2: ENAH (Q8N8S7)
Protein enabled homolog
Gene: ENAH

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29568061
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0030175 - filopodium
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 586 Hs			1 591
+	Hs
		547137 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		MINK1_HUMAN (113-575): 1.26e-34: 142: 15.12
+	Hs
		547270 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		TNIK_HUMAN (129-587): 5.09e-30: 128: 17.86
+	Hs
		547074 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		ITSN1_HUMAN (124-263): 2.96e-29: 125: 37.59
+	Hs
		159872 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		HGS_HUMAN (90-385): 6.31e-28: 120: 22.22
+	Hs
		719777 RADI_HUMAN (1-586): 7.83e-165: 484: 76.28		MYO10_HUMAN (182-480): 4.53e-25: 112: 14.15
+	Hs
		547263 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		SWP70_HUMAN (84-269): 5.97e-14: 76.9: 25.00
+	Hs
		640132 MOES_HUMAN (1-586): 4.45e-161: 474: 72.70		TITIN_HUMAN (81-495): 1.61e-25: 114: 11.06
+	Hs
		547250 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		ITSN2_HUMAN (102-259): 2.05e-10: 66.1: 25.63
+	Hs
		297816 RADI_HUMAN (1-586): 7.83e-165: 484: 76.28		K0754_HUMAN (249-591): 1.4e-12: 73.4: 10.63
+	Hs
		159909 MERL_HUMAN (2-586): 3.18e-146: 436: 44.37		HGS_HUMAN (90-385): 6.31e-28: 120: 22.22
+	Hs
		1233547 E41LA_HUMAN (1-576): 5.03e-116: 361: 16.47		MINK1_HUMAN (113-575): 1.26e-34: 142: 15.12
+	Dm
		1101464 Q2M1E6_DROME (3-567): 3.37e-114: 368: 20.07		HRS_DROME (174-380): 6.01e-25: 111: 24.66
+	Hs
		1049684 E41L3_HUMAN (2-466): 2.17e-114: 367: 22.83		EIF3A_HUMAN (89-278): 2e-23: 107: 21.15
+	Hs
		297842 E41LA_HUMAN (1-576): 5.03e-116: 361: 16.47		K0754_HUMAN (249-591): 1.4e-12: 73.4: 10.63
+	Hs
		640244 PTN3_HUMAN (18-295): 2.55e-32: 134: 31.82		EIF3A_HUMAN (89-278): 2e-23: 107: 21.15